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1609534-59-9

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1609534-59-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1609534-59-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,0,9,5,3 and 4 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1609534-59:
(9*1)+(8*6)+(7*0)+(6*9)+(5*5)+(4*3)+(3*4)+(2*5)+(1*9)=179
179 % 10 = 9
So 1609534-59-9 is a valid CAS Registry Number.

1609534-59-9Downstream Products

1609534-59-9Relevant articles and documents

Combinatorially designed lipid-like nanoparticles for intracellular delivery of cytotoxic protein for cancer therapy

Wang, Ming,Alberti, Kyle,Sun, Shuo,Arellano, Carlos Luis,Xu, Qiaobing

supporting information, p. 2893 - 2898 (2014/04/03)

An efficient and safe method to deliver active proteins into the cytosol of targeted cells is highly desirable to advance protein-based therapeutics. A novel protein delivery platform has been created by combinatorial design of cationic lipid-like materials (termed lipidoids ), coupled with a reversible chemical protein engineering approach. Using ribonuclease A (RNase A) and saporin as two representative cytotoxic proteins, the combinatorial lipidoids efficiently deliver proteins into cancer cells and inhibit cell proliferation. A study of the structure-function relationship reveals that the electrostatic and hydrophobic interactions between the lipidoids and the protein play a vital role in the formation of protein-lipidoid nanocomplexes and intracellular delivery. A representative lipidoid (EC16-1) protein nanoparticle formulation inhibits cell proliferation in vitro and suppresses tumor growth in a murine breast cancer model.

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