1609960-67-9

Basic information

• Product Name: C₂₁H₂₁F₃N₄O₄S
• Synonyms: C₂₁H₂₁F₃N₄O₄S
• CAS NO: 1609960-67-9
• Molecular Weight: 482.483
• Mol File: 1609960-67-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₂₁H₂₁F₃N₄O₄S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₂₁F₃N₄O₄S(1609960-67-9)
• EPA Substance Registry System: C₂₁H₂₁F₃N₄O₄S(1609960-67-9)

Safety Data

• Hazardous Substances Data: 1609960-67-9(Hazardous Substances Data)

Upstream product

• 1332712-64-7 (S)-4-fluoro-2-(tetrahydrofuran-3-yloxy)aniline 
• 1609963-02-1 N'-[2-cyano-3-(difluoromethoxy)-5-[[dimethyl(oxo)-λ⁶-sulfanylidene]amino]phenyl]-N,N-dimethylformamidine 
• 1609963-01-0 N'-(5-bromo-2-cyano-3-fluorophenyl)-N,N-dimethylformamidine 
• 1609963-00-9 N'-(5-bromo-2-cyano-3-fluorophenyl)-N,N-dimethylformamidine 
• 1609962-99-3 N′-[2-cyano-5-[[dimethyl(oxo)-λ⁶-sulfanylidene]amino]-3-hydroxyphenyl]-N,N-dimethylformamidine 
• 1609962-87-9 N'-(5-bromo-2-cyano-3-fluoro-phenyl)-N,N-dimethyl-formamidine 
• 123843-67-4 4-bromo-2,6-difluorobenzonitrile 
• 1279865-14-3 2-amino-4-bromo-6-fluoro-benzonitrile 

Relevant articles and documents

SULFOXIMINE SUBSTITUTED QUINAZOLINES FOR PHARMACEUTICAL COMPOSITIONS

This invention relates to novel sulfoximine substituted quinazoline derivatives of formula (I), wherein Ar, R1 and R2 are as defined in the description and claims, and their use as MNK1 (MNK1a or MNK1b) and/or MNK2 (MNK2a or MNK2b) kinase inhibitors, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment or amelioration of MNK1 (MNK1a or MNK1b) and/or MNK2 (MNK2a or MNK2b) mediated disorders.