161045-48-3

Upstream product

• 582-52-5 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 
• 161045-46-1 3-O-allyl-6-O-benzoyl-1,2-O-isopropylidene-5-O-methanesulfonyl-α-D-glucofuranose 
• 161045-47-2 3-O-allyl-5,6-anhydro-1,2-O-isopropylidene-β-L-idofuranose 
• 91882-92-7 3-O-allyl-1,2-O-isopropylidene-α-D-glucofuranose 
• 20316-77-2 (3aR,5R,6S,6aR)-6-(allyloxy)-5-((R)-2,2-dimethyl[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydrofuro[2,3-d][1,3]dioxole 

Downstream Products

• 161045-49-4 methyl 3-O-allyl-6-azido-5-O-benzyl-6-deoxy-α-L-idofuranoside 
• 161045-50-7 methyl 3-O-allyl-6-azido-5-O-benzyl-6-deoxy-β-L-idofuranoside 
• 130539-14-9 2,3-di-O-benzyl-N-benzyloxycarbonyl-1,5-dideoxy-1,5-imino-D-glucitol 
• 161045-52-9 4-O-allyl-2-O-benzyl-N-benzyloxycarbonyl-1,5-dideoxy-1,5-imino-D-gulcitol 
• 161045-53-0 N-benzyloxycarbonyl-2,3-di-O-benzyl-6-O-tert-butyldiphenylsilyl-1,5-dideoxy-1,5-imino-D-gulcitol 
• 372493-97-5 4-O-allyl-N-benzyloxycarbonyl-2,3-di-O-benzyl-6-O-tert-butyldiphenylsilyl-1,5-dideoxy-1,5-imino-D-gulcitol 
• 161045-56-3 4-O-(2-acetamido-3,4-di-O-benzyl-2-deoxy-6-O-p-methoxybenzyl-α-D-glucopyranosyl)-N-benzyloxycarbonyl-2,3-di-O-benzyl-1,5-dideoxy-1,5-imino-D-gulcitol 
• 372494-13-8 benzyl 3-O-(2-acetamido-3,4-di-O-benzyl-2-deoxy-α-D-glucopyranosyl)-N-benzyloxycarbonyl-4,5-di-O-benzyl-2,6-dideoxy-2,6-imino-L-gulonate 
• 161045-57-4 benzyl 3-O-(2-acetamido-3,4-di-O-benzyl-2-deoxy-6-O-p-methoxybenzyl-α-D-glucopyranosyl)-N-benzyloxycarbonyl-4,5-di-O-benzyl-2,6-dideoxy-2,6-imino-L-gulonate 
• 372494-07-0 4-O-(2-acetamido-3,4-di-O-benzyl-2-deoxy-6-O-p-methoxybenzyl-α-D-glucopyranosyl)-N-benzyloxycarbonyl-2,3-di-O-benzyl-6-O-tert-butyldiphenylsilyl-1,5-dideoxy-1,5-imino-D-gulcitol 
• 161045-55-2 4-O-(2-azido-3,4-di-O-benzyl-2-deoxy-6-O-p-methoxybenzyl-α-D-glucopyranosyl)-N-benzyloxycarbonyl-2,3-di-O-benzyl-6-O-tert-butyldiphenylsilyl-1,5-dideoxy-1,5-imino-D-gulcitol 
• 372493-94-2 methyl 3-O-allyl-5-O-benzyl-N-benzyloxycarbonyl-2,6-dideoxy-2,6-imino-β-L-gulofuranoside 
• 161106-75-8 methyl 3-O-allyl-5-O-benzyl-N-benzyloxycarbonyl-2,6-dideoxy-2,6-imino-α-L-gulofuranoside 
• 372494-16-1 4-O-allyl-N-benzyloxycarbonyl-2,3-di-O-benzyl-1,5-dideoxy-1,5-imino-D-gulcitol 

Relevant academic research and scientific papers

Design and synthesis of a heparanase inhibitor with pseudodisaccharide structure

Aza-analogue of the basic disaccharide unit of heparane sulfate was designed as a potent inhibitor against heparanase produced by solid tumors cell, and synthesized via a coupling reaction of phenyl 2-azide-1-thio-D-glucopyranoside derivatives with a partially protected 1-deoxynojirimycin derived from D-glucose. The azapseudodisaccharide inhibited tumor cell heparanase with IC50 value of 58-63 μM.