161060-38-4

Basic information

• Product Name: [2-Hydroxy-2-(4-isopropyl-5-oxo-2,5-dihydro-oxazol-2-yl)-1-phenyl-ethyl]-carbamic acid tert-butyl ester
• Synonyms: [2-Hydroxy-2-(4-isopropyl-5-oxo-2,5-dihydro-oxazol-2-yl)-1-phenyl-ethyl]-carbamic acid tert-butyl ester
• CAS NO: 161060-38-4
• Molecular Weight: 362.426
• Mol File: 161060-38-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: [2-Hydroxy-2-(4-isopropyl-5-oxo-2,5-dihydro-oxazol-2-yl)-1-phenyl-ethyl]-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [2-Hydroxy-2-(4-isopropyl-5-oxo-2,5-dihydro-oxazol-2-yl)-1-phenyl-ethyl]-carbamic acid tert-butyl ester(161060-38-4)
• EPA Substance Registry System: [2-Hydroxy-2-(4-isopropyl-5-oxo-2,5-dihydro-oxazol-2-yl)-1-phenyl-ethyl]-carbamic acid tert-butyl ester(161060-38-4)

Safety Data

• Hazardous Substances Data: 161060-38-4(Hazardous Substances Data)

Upstream product

• 140196-38-9 1,1-dimethyl (2-oxo-1-phenylethyl)carbamate 
• 4526-83-4 4-(1-methylethyl)-2-oxazolin-5-one 

Downstream Products

• 161060-39-5 (2S,3S)-2-acetyloxy-3-(benzoylamino)-3-phenylpropanoic acid methyl ester 
• 151764-53-3 (2R,3R)-(-)-2-hydroxy-3-(benzoylamino)-3-phenylpropanoic acid methyl ester 
• 144541-45-7 methyl (2S,3S)-3-benzoylamino-2-hydroxy-3-phenylpropanoate 
• 32981-85-4 syn-(+/-)-2-hydroxy-3-(benzoylamino)-3-phenylpropanoic acid methyl ester 
• 161167-76-6 2-(3-tert-Butoxycarbonylamino-2-hydroxy-3-phenyl-propionylamino)-3-methyl-butyric acid methyl ester 

Relevant articles and documents

A chemoenzymatic approach to chiral phenylisoserinates using 4-isopropyl-2-oxazolin-5-one as masked umpoled synthon for hydroxycarbonyl anion

The aldol adduct between the anion of 4-isopropyl-2-oxazolin-5-one with racemic N-(tertbutoxycarbonyl)-phenylglycinal underwent concomitant isomerization and ring cleavage under mild basic conditions producing the racemic dipeptide N-Boc-phenylisoserine-v