A chemoenzymatic approach to chiral phenylisoserinates using 4-isopropyl-2-oxazolin-5-one as masked umpoled synthon for hydroxycarbonyl anion

DOI: 10.1016/0040-4039(94)88490-0

Source and publish data:

Tetrahedron Letters p. 9289 - 9292 (1994)

Update date:2022-07-30

Topics:

Authors:

Barco, Achille

Benetti, Simonetta

De Risi, Carmela

Pollini, Gian P.

Romagnoli, Romeo

Zanirato, Vinicio

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(94)88490-0

The aldol adduct between the anion of 4-isopropyl-2-oxazolin-5-one with racemic N-(tertbutoxycarbonyl)-phenylglycinal underwent concomitant isomerization and ring cleavage under mild basic conditions producing the racemic dipeptide N-Boc-phenylisoserine-v

Full text of DOI:10.1016/0040-4039(94)88490-0

Products guided by the article

Product name:[2-Hydroxy-2-(4-isopropyl-5-oxo-2,5-dihydro-oxazol-2-yl)-1-phenyl-ethyl]-carbamic acid tert-butyl ester

Cas No:161060-38-4

R&D Labs maybe for 161060-38-4

Xiamen Goodhealth Pharmchem Co., Ltd.

Contact:0086-592-2097683

Address:404R No.2 54# Minzu Rd., Xiamen, China
Weifang Arylchem Chemical Co., LTD

Contact:86-536-5217866

Address:Development Zone, Shouguang, Shandong Province
SHANDONG QINGYUNCHANGXIN CHEMICAL SCIENCE-TECH CO.,LTD

Contact:86-21-60560171

Address:1689Donghuan Rade,Qingyun County, Dezhou City, Shandong,China
Weifang Adde Economic And Trade Co.,LTD.

Contact:86-536-8885548

Address:Room 1402,Wanda Plaza B Block,No.958,Yuanfei Road,Kuiwen District
Xi'an Costrong Pharmaceutical Co., Ltd.

Contact:029- 68576496

Address:Room 2004,Shuibao Building,No.190,South Erhuan Rd, Yanta District,Xi'an,Shaan Xi,China

Relevant to this article

Efficient method for the synthesis of 1,2,3-triazole functionalized isoxazolidine derivatives by 1,3-dipolar cycloaddition of nitrones with terminal olefins

Doi:10.1080/00397911.2016.1271133
(2017)
Total Synthesis of L-156,373 and an oxoPiz Analogue via a Submonomer Approach

Doi:10.1021/acs.orglett.8b00912
(2018)
Use of Hydrogen Bonds To Control Molecular Aggregation. Behavior of Dipyridones and Pyridone-Pyrimidones Designed To Form Cyclic Triplexes

Doi:10.1021/jo00110a050
(1995)
Novel domino reactions for the efficient synthesis of 5,6-dihydro-1,4,2- oxathiazines

Doi:10.1016/j.tetlet.2014.05.062
(2014)
Synthesis, identification and in vitro biological evaluation of some novel 5-imidazopyrazole incorporated pyrazoline and isoxazoline derivatives

Doi:10.1039/c4nj00244j
(2014)
Zeolite-catalyzed method for the preparation of 2,3-dihydroquinazolin-4(1H) -ones

Doi:10.1080/00397911.2014.894525
(2014)

Article Doi