1611-03-6

Usage

Uses

Used in Food Industry:
3,5-DI-TERT-BUTYL-4-HYDROXYPHENYLACETIC ACID is used as a preservative in the food industry to prevent the oxidation of fats and oils, thereby extending the shelf life of food products.
Used in Plastics and Rubber Industry:
In the production of plastics, rubber, and other industrial materials, 3,5-DI-TERT-BUTYL-4-HYDROXYPHENYLACETIC ACID is used as an antioxidant to prevent degradation caused by oxidation, ensuring the longevity and stability of these materials.
Used in Pharmaceutical Industry:
3,5-DI-TERT-BUTYL-4-HYDROXYPHENYLACETIC ACID is used as a potential therapeutic agent in the pharmaceutical industry due to its anti-inflammatory and antioxidant properties, offering potential benefits in the treatment of various conditions.

InChI:InChI=1/C16H24O3/c1-15(2,3)11-7-10(9-13(17)18)8-12(14(11)19)16(4,5)6/h7-8,19H,9H2,1-6H3,(H,17,18)/p-1

Upstream product

• 1611-07-0 3,5-Di-tert-butyl-4-hydroxyphenylacetonitrile 
• 156-38-7 4-hydroxyphenylacetate 
• 540-88-5 acetic acid tert-butyl ester 
• 2091-51-2 4-(bromomethyl)-2,6-di-tert-butylphenol 
• 128-37-0 2,6-di-tert-butyl-4-methyl-phenol 
• 28441-16-9 (3,5-di-tert-butyl-4-hydroxyphenyl)-2-oxoethyl acetate 
• 124-38-9 carbon dioxide 
• 955-01-1 3,5-di-tert-butyl-4-hydroxy benzyl chloride 

Downstream Products

• 17750-38-8 4-Hydroxy-3,5-di-tert.-butyl-phenyl-essigsaeure-N-<2-(3-methoxy-4-benzyloxy-phenyl)-aethyl>-amid 
• 190833-84-2 ethyl 4-({[(4-hydroxy-3,5-di-tert-butylphenyl)acetyl]amino}sulfonyl)benzoate 
• 190833-99-9 4-({[(4-chlorophenyl)sulfonyl]amino}carbonyl)benzoyl-N-ε-[(4-hydroxy-3,5-di-tert-butylphenyl)acetyl]-Lys-OCH3 
• 6386-40-9 ethyl 4-hydroxy-3,5-di-tert-butylphenylacetate 
• 146794-78-7 (3,5-di-tert-butyl-4-hydroxy-phenyl)-acetic acid isopropyl ester 
• 209973-23-9 (3,5-di-tert-butyl-4-hydroxy-phenyl)-acetic acid butyl ester 
• 54117-97-4 3,5-di-tert-butyl-4-hydroxyphenylacetic acid tert-butyl ester 
• 183721-39-3 N,N-Diethyl-2-(3,5-di-tert-butyl-4-hydroxyphenyl)acetamide 
• 1195777-21-9 (3,5-di-tert-butyl-4-hydroxyphenyl)-acetic acid 2-butyl-5-chloro-3-[2'-(2-trityl-2H-tetrazol-5-yl)biphenyl-4-ylmethyl]-3H-imidazol-4-yl methyl ester 
• 161787-69-5 4-({[(4-chlorophenyl)sulfonyl]amino}carbonyl)benzoyl-N-ε-[(4-hydroxy-3,5-di-tert-butylphenyl)acetyl]-Lys-OH 
• 190833-96-6 ethyl 4-[({[4-chloro-3-({[(4-hydroxy-3,5-di-tert-butylphenyl)acetyl]amino}sulfonyl)phenyl]carbonyl}amino)sulfonyl]benzoate 
• 161787-52-6 4-[({[4-chloro-3-({[(4-hydroxy-3,5-di-tert-butylphenyl)acetyl]amino}sulfonyl)phenyl]carbonyl}amino)sulfonyl]benzoic acid 
• 190833-93-3 3-({[(4-hydroxy-3,5-di-tert-butylphenyl)acetyl]amino}sulfonyl)-4-chlorobenzoic acid 
• 161787-49-1 4-({[(4-hydroxy-3,5-di-tert-butylphenyl)acetyl]amino}sulfonyl)benzoic acid 

Relevant academic research and scientific papers

Mechanism of photosolvolytic rearrangement of p-hydroxyphenacyl esters: Evidence for excited-state intramolecular proton transfer as the primary photochemical step

The photosolvolytic rearrangement of a variety of p-hydroxyphenacyl esters and related compounds 7-16 has been studied in solutions with up to 50% aqueous content, using product studies, triplet quenchers, and nanosecond laser flash photolysis. The p-hydroxyphenacyl moiety has recently been proposed as a new and efficient photoactivated protecting group in aqueous solution. Practical applications have been demonstrated, but much less is known about the mechanism of photoreaction. Our data support a novel mechanism in which the primary photochemical step from the singlet excited state is formal intramolecular proton transfer from the phenolic proton to the carbonyl oxygen of the distal ketone, mediated by solvent water, to generate the corresponding p-quinone methide phototautomer. This reactive intermediate (most likely in its excited state) subsequently expels the carboxylic acid with concerted rearrangement to a spiroketone intermediate, which subsequently leads to the final observed product, p- hydroxyphenylacetic acid. An alternative mechanism is deprotonation of the phenolic proton, loss of the carboxylate, and rearrangement to the spiroketone, all in one concerted primary photochemical step from S1.

Dual inhibition of human leukocyte elastase and lipid peroxidation: In vitro and in vivo activities of azabicyclo[2.2.2]octane and perhydroindole derivatives

A series of potent and selective human leukocyte elastase (HLE) inhibitors of the Val-Pro-Val type has been developed. Initially, the central proline residue was replaced by nonnatural amino acids Phi ((2S,3aS,7aS)- perhydroindole-2-carboxylic acid) and A