16115-82-5

Usage

Uses

Used in Pharmaceutical Synthesis:
3-Amino-4-nitropyrazole is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to form heterocyclic compounds, which are integral to the development of new drugs with a range of therapeutic applications.
Used in Agrochemical Synthesis:
In the agrochemical industry, 3-Amino-4-nitropyrazole is utilized as a building block for the creation of compounds that have applications in crop protection and pest control, enhancing agricultural productivity and crop safety.
Used in Organic Chemistry Reactions:
3-Amino-4-nitropyrazole serves as a reagent in organic chemistry, facilitating specific reactions that are crucial for the synthesis of complex organic molecules, including those with potential applications in material science and specialty chemicals.
Used in Medicinal Chemistry Research:
3-Amino-4-nitropyrazole is employed in medicinal chemistry research to explore its potential in the development of new drugs. Its high reactivity allows for the creation of novel molecular structures that could address unmet medical needs or improve upon existing treatments.

InChI:InChI=1/C3H4N4O2/c4-3-2(7(8)9)1-5-6-3/h1H,(H3,4,5,6)

Upstream product

• 65190-36-5 4-nitro-1H-pyrazole-3-carboxamide 

Downstream Products

• 329207-51-4 ethyl 7-methyl-3-nitropyrazolo[1,5-a]pyrimidin-6-carboxylate 
• 35852-75-6 3-chloro-4-nitro-1H-pyrazole 
• 148777-84-8 3-nitro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine 
• 896467-52-0 2-(4-nitro-1H-pyrazol-3-yl)-isoindole-1,3-dione 

Relevant academic research and scientific papers

Nitropyrazoles 8. 3(5)-Amino-4-nitropyrazole: convenient synthesis and study of nitration

A new preparative method for the synthesis of 3(5)-amino-4-nitropyrazole starting from accesible 3(5)-methylpyrazole has been elaborated.Nitration of the former affords 3(5)-nitramino-4-nitropyrazole or 1,4-dinitro-3-aminopyrazole, depending on the reaction conditions. - Key words: 3(5)-amino-4-nitropyrazole, aminonitropyrazoles, nitration.

FUSED PYRIMIDINE COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF

The present disclosure relates to a class of fused pyrimidine compounds of Formula I, their stereoisomers, tautomers, pharmaceutically acceptable salts, polymorphs, solvates, and hydrates thereof. The present disclosure also relates to a process of preparation of these fused pyrimidine compounds, and to pharmaceutical compositions containing them.

PYRROLOPYRIMIDINE COMPOUNDS, USE AS INHIBITORS OF THE KINASE LRRK2, AND METHODS FOR PREPARATION THEREOF

The present disclosure is concerned with certain pyrrolopyrimidine compounds that are capable of inhibiting certain protein kinases, and especially the leucine-rich repeat kinase 2 (LRRK2) protein. Compounds of the present disclosure can be used to treat

7-SUBSTITUTED 3-NITRO-PYRAZOLO `1,5-A! PYRIMIDINES

The present invention relates to compounds of Formula (I): wherein R1 is as defined in the claims. The compounds have specific affinity for the GABAA receptor and are therefore useful in the treatment and prevention of diseases modul