161150-58-9

Upstream product

• 161150-57-8 [1-(tert-butyldiphenylsilanyloxymethyl)-2-oxopropyl]carbamic acid benzyl ester 
• 149-73-5 trimethyl orthoformate 
• 161150-55-6 (2R,3R)-2-(benzyloxycarbonyl)amino-1,3-butanediol 
• 161150-56-7 [1-(tert-butyldiphenylsilanyloxymethyl)-2-hydroxypropyl]carbamic acid benzyl ester 
• 19728-63-3 N-benzyloxycarbonyl-L-treonine 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 560130-31-6 (2R)-3-(benzyloxycarbonyl)amino-3,3-dimethoxybutanol 
• 955135-25-8 {[1-(tert-butyldiphenylsilanyloxymethyl)-2,2-dimethoxypropylcarbamoyl]methyl}carbamic acid benzyl ester 
• 955135-26-9 [(1-hydroxymethyl-2,2-dimethoxypropylcarbamoyl)methyl]carbamic acid benzyl ester 
• 955135-32-7 {1-[1-(tert-butyldiphenylsilanyloxymethyl)-2,2-dimethoxypropylcarbamoyl]-2-hydroxyethyl}carbamic acid benzyl ester 
• 161275-55-4 (3R,4R,5S)-2-[(Z)-1-benzoylamino-1-[1-(t-butyldiphenylsiloxy)methyl-2,2-dimethoxypropyl]-carbamoyl]methylidene-3,4-dibenzyloxy-1-(prop-2-en-1-yloxy)carbonyl-5-(methanesulfonyloxy)methylpyrrolidine 
• 161150-62-5 (3R,4R,5S)-2-[(E)-1-benzoylamino-1-[1-(t-butyldiphenylsiloxy)methyl-2,2-dimethoxypropyl]-carbamoyl]methylidene-3,4-dibenzyloxy-1-(prop-2-en-1-yloxy)carbonyl-5-(methanesulfonyloxy)methylpyrrolidine 
• 161275-56-5 (3R,4R,5S)-2-[(Z)-1-benzoylamino-1-[1-hydroxymethyl-2,2-dimethoxypropyl]-carbamoyl]methylidene-3,4-dibenzyloxy-1-(prop-2-en-1-yloxy)carbonyl-5-(methanesulfonyloxy)methylpyrrolidine 
• 161150-63-6 (3R,4R,5S)-2-[(E)-1-benzoylamino-1-[1-hydroxymethyl-2,2-dimethoxypropyl]-carbamoyl]methylidene-3,4-dibenzyloxy-1-(prop-2-en-1-yloxy)carbonyl-5-(methanesulfonyloxy)methylpyrrolidine 
• 161275-57-6 (3R,4R,5S)-2-[(Z)-1-benzoylamino-1-[1-formyl-2,2-dimethoxypropyl]-carbamoyl]methylidene-3,4-dibenzyloxy-1-(prop-2-en-1-yloxy)carbonyl-5-(methanesulfonyloxy)methylpyrrolidine 
• 161150-64-7 (3R,4R,5S)-2-[(E)-1-benzoylamino-1-[1-formyl-2,2-dimethoxypropyl]-carbamoyl]methylidene-3,4-dibenzyloxy-1-(prop-2-en-1-yloxy)carbonyl-5-(methanesulfonyloxy)methylpyrrolidine 
• 560130-33-8 (Z)-3-(benzyloxycarbonyl)amino-4-hydroxybut-3-en-2-one 
• 560130-27-0 (2R)-3-(benzyloxycarbonyl)amino-3,3-dimethoxybutanal 
• 161150-59-0 (3R)-3-amino-4-(t-butyldiphenylsilyl)oxy-2-butanone dimethyl acetal 

Relevant academic research and scientific papers

Synthesis of functional "top-half" partial structures of azinomycin A and B

(Chemical Equation Presented) The design and synthesis of a detailed series of functional "top-half substructures of azinomycin A and B is described.

Synthetic studies of carzinophilin. Part 2: Synthesis of 3,4-dibenzyloxy-2-methylidene-1-azabicyclo[3.1.0]hexane systems corresponding to the C1-C17 fragment of carzinophilin

A model compound bearing the C1-C17 fragment of carzinophilin was synthesized. The synthesis involved coupling reaction of a cyclic thioimidate with the 4H-oxazol-5-one derivative, ring-opening of the 4H-oxazol-5-one to furnish a dehydropeptide system, elaboration of the C1-C6 enolamide, and construction of the aziridine ring as key steps.

A Novel Synthesis of the C1-C17 Fragment of Carzinophilin

The title synthesis was achieved by featuring i) condensation of the 2-methylthio-Δ1-pyrroline (C8-C13 moiety) with the Δ2-oxazolin-5-one (C6,C7,N16, and C17 moiety), ii) activation of the Δ2-oxazolin-5-one system toward n