161152-04-1Relevant articles and documents
Synthesis and evaluation of estrogen agonism of diaryl 4,5- dihydroisoxazoles, 3-hydroxyketones, 3-methoxyketones, and 1,3-diketones: A compound set forming a 4D molecular library
Pulkkinen, Juha T.,Honkakoski, Paavo,Per?kyl?, Mikael,Berczi, Istvan,Laatikainen, Reino
supporting information; experimental part, p. 3562 - 3571 (2009/04/06)
In this paper, the preparation and systematic evaluation of estrogen receptor α (ERα) and estrogen receptor β (ERβ) activities of some diaryl-1,3-diones and their synthetic intermediates, diaryl-4,5-dihydroisoxazoles, diaryl-3-hydroxyketones, diaryl-3-met
3-Unsubstituted 1,5-diaryl-2,4-pentanediones and -4-methoxy-2-pentanones: Synthesis via corresponding 3-hydroxy ketones generated from 2-isoxazolines
Pulkkinen, Juha T.,Vepsaelaeinen, Jouko J.
, p. 8604 - 8609 (2007/10/03)
Aryl acetaldoximes are reacted with allylarenes in the presence of sodium hypochlorite to give 3,5-bis(arylmethyl)-2-isoxazolines which are then converted to 1,5-diaryl-4-hydroxy-2-pentanones by a reductive hydrogenation in the presence of water. These in
A General Route to 3-Unsubstituted 1,5-Diaryl-2,4-pentanediones and -4-Methoxy-2-pentanones
Pulkkinen, Juha,Vepsaelaeinen, Jouko,Laatikainen, Reino
, p. 9749 - 9750 (2007/10/02)
2-Isoxazolines are converted to corresponding 3-hydroxyketones which are used as precursors to produce new 3-unsubstituted 1,5-diaryl-2,4-pentanediones and -4-methoxy-2-pentanones.