39095-38-0

Basic information

• Product Name: Corey-Kim reagent
• Synonyms: Corey-Kim reagent;N-Chlorosuccinimide-Dimethyl Sulfide
• CAS NO: 39095-38-0
• Molecular Formula: C₆H₁₀NO₂S*Cl
• Molecular Weight: 195.6671
• Mol File: 39095-38-0.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Corey-Kim reagent(CAS DataBase Reference)
• NIST Chemistry Reference: Corey-Kim reagent(39095-38-0)
• EPA Substance Registry System: Corey-Kim reagent(39095-38-0)

Safety Data

• Hazardous Substances Data: 39095-38-0(Hazardous Substances Data)

Upstream product

• 128-09-6 N-chloro-succinimide 
• 75-18-3 dimethylsulfide 

Downstream Products

• 82661-89-0 3-Cyano-3-methyl-2-(methylsulfanylmethylimino-methylene)-3-phenyl-propionic acid methyl ester 
• 82650-40-6 2,3-Dicyano-3-methyl-2-methylsulfanylmethyl-3-phenyl-propionic acid methyl ester 
• 33932-89-7 2-dimethylsulfuranylidene-5,5-dimethylcyclohexane-1,3-dione 
• 15424-14-3 N-phenylbenzohydrazonoyl chloride 
• 123-56-8 Succinimide 
• 2373-51-5 chloro-methylsulfanyl-methane 
• 16184-95-5 2,6-Dimethyl-6-(methylthiomethyl)-2,4-cyclohexadien-1-on 
• 35357-68-7 N-benzyl-S,S-dimethylsulfilimmonium chloride 
• 33313-98-3 2,6,6-tris(methylthiomethyl)-2,4-cyclohexadien-1-one 
• 15021-43-9 dimethylsulfonium 1-benzoyl-2-oxopropylide 
• 10353-20-5 2,6-bis(methylthiomethyl)-4,6-dimethyl-2,4-cyclohexadien-1-one 
• 34025-26-8 2-(dimethyl-λ⁴-sulfaneylidene)-1,3-diphenylpropane-1,3-dione 

Relevant articles and documents

Synthesis and insecticidal activity of spinosyn analogs functionally altered at the 2'-, 3'- and 4'-positions of the rhamnose moiety

In an effort to increase the insecticidal activity of the spinosyn family of naturally occurring macrolides, the 2'-, 3'- and 4'-O-desmethyl-O-acetyl analogs and the 2'-, 3'-, and 4'-O-desmethoxy analogs have been synthesized. These analogs were prepared synthetically from the minor spinosyn factors H, J, K, L and Q either via direct acylation of the corresponding factor or deoxygenation of an intermediate xanthate. The acylated analogs were all more potent insecticides against Heliothis virescens larvae than their respective parent factors, but not as potent as spinosyns A or D. The deoxy analogs were also more potent insecticides than their respective parent factors. The 2'-desmethoxy analogs showed, for the first time, analogs with insecticidal potency against H. virescens greater than that of spinosyns A and D, indicating that polarity is not well tolerated in the rhamnose moiety of spinosyn A.

Investigation of the stability of the Corey-Kim intermediate

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3-Unsubstituted 1,5-diaryl-2,4-pentanediones and -4-methoxy-2-pentanones: Synthesis via corresponding 3-hydroxy ketones generated from 2-isoxazolines

Aryl acetaldoximes are reacted with allylarenes in the presence of sodium hypochlorite to give 3,5-bis(arylmethyl)-2-isoxazolines which are then converted to 1,5-diaryl-4-hydroxy-2-pentanones by a reductive hydrogenation in the presence of water. These in