1612263-55-4Relevant academic research and scientific papers
Correction to: Nickel-catalyzed enantioselective reductive cross-coupling of styrenyl aziridines (Journal of the American Chemical Society (2017) 139 (5688-5691) DOI: 10.1021/jacs.7b03448)
Woods, Brian P.,Orlandi, Manuel,Huang, Chung-Yang Dennis,Sigman, Matthew S.,Doyle, Abigail G.
, p. 7744 - 7745 (2018/06/26)
Table of Contents. The enantiomer of the BiOx ligand that delivers the indicated absolute configuration of product is (R,R)-(4-heptyl)BiOx. The corrected graphic is shown below: Page 5690. The absolute configuration of ligand L7 (4-heptyl- BiOx) was misas
Nickel-Catalyzed Enantioselective Reductive Cross-Coupling of Styrenyl Aziridines
Woods, Brian P.,Orlandi, Manuel,Huang, Chung-Yang,Sigman, Matthew S.,Doyle, Abigail G.
, p. 5688 - 5691 (2017/05/04)
A Ni-catalyzed reductive cross-coupling of styrenyl aziridines with aryl iodides is reported. This reaction proceeds by a stereoconvergent mechanism and is thus amenable to asymmetric catalysis using a chiral bioxazoline ligand for Ni. The process allows
Pd/NHC-catalyzed enantiospecific and regioselective suzuki-miyaura arylation of 2-arylaziridines: Synthesis of enantioenriched 2-arylphenethylamine derivatives
Takeda, Youhei,Ikeda, Yuki,Kuroda, Akinobu,Tanaka, Shino,Minakata, Satoshi
supporting information, p. 8544 - 8547 (2014/07/07)
A palladium-catalyzed stereospecific and regioselective cross-coupling of enantiopure 2-arylaziridines with arylboronic acids under mild conditions to construct a tertiary stereogenic center has been developed. N-heterocyclic carbene (NHC) ligands efficiently promote the coupling, suppressing β-hydride elimination. The enantiospecific cross-coupling allowed us for preparation of a series of biologically important 2-arylphenethylamine derivatives in an enantiopure form.
