1613145-24-6

Basic information

• Product Name: (4-fluorophenyl)carbamoyl azide
• Synonyms: (4-fluorophenyl)carbamoyl azide
• CAS NO: 1613145-24-6
• Molecular Weight: 180.141
• Mol File: 1613145-24-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (4-fluorophenyl)carbamoyl azide(CAS DataBase Reference)
• NIST Chemistry Reference: (4-fluorophenyl)carbamoyl azide(1613145-24-6)
• EPA Substance Registry System: (4-fluorophenyl)carbamoyl azide(1613145-24-6)

Safety Data

• Hazardous Substances Data: 1613145-24-6(Hazardous Substances Data)

Upstream product

• 459-57-4 4-fluorobenzaldehyde 
• 5157-58-4 2,2-dichloro-1-(4-fluorophenyl)-ethan-1-one 
• 766-98-3 1-ethynyl-4-fluorobenzene 
• 4648-54-8 trimethylsilylazide 
• 63131-29-3 methyl 4-fluorobenzoyl acetate 

Relevant articles and documents

Pathways in the Degradation of Geminal Diazides

The degradation of geminal diazides is described. We show that diazido acetates are converted into tetrazoles through the treatment with bases. The reaction of dichloro ketones with azide anions provides acyl azides, through in situ formation of diazido ketones. We present experimental and theoretical evidence that both fragmentations may involve the generation of acyl cyanide intermediates. The controlled degradation of terminal alkynes into amides (by loss of one carbon) or ureas (by loss of two carbons) is also shown.

Ceric ammonium nitrate (CAN) catalyzed modification of ketones via two C-C bond cleavages with the retention of the oxo-group

A simple ceric ammonium nitrate (CAN) catalyzed functionalization of ketones through double C-C bond cleavage strategy has been disclosed. This reaction provides a mild, practical method toward carbamoyl azides, which are versatile intermediates and building blocks in organic synthesis. Based on relevant mechanistic studies, a unique and plausible C-C bond and N-O bond cleavage process is proposed, where the oxyamination intermediate plays an important role in this reaction.