1613148-57-4

Basic information

• Product Name: N,N-bis(tert-butoxycarbonyl)-3-(1-(2,5-difluorophenyl)ethoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine
• Synonyms: N,N-bis(tert-butoxycarbonyl)-3-(1-(2,5-difluorophenyl)ethoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine
• CAS NO: 1613148-57-4
• Molecular Weight: 576.446
• Mol File: 1613148-57-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N,N-bis(tert-butoxycarbonyl)-3-(1-(2,5-difluorophenyl)ethoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-bis(tert-butoxycarbonyl)-3-(1-(2,5-difluorophenyl)ethoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine(1613148-57-4)
• EPA Substance Registry System: N,N-bis(tert-butoxycarbonyl)-3-(1-(2,5-difluorophenyl)ethoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine(1613148-57-4)

Safety Data

• Hazardous Substances Data: 1613148-57-4(Hazardous Substances Data)

Upstream product

• 1613148-56-3 5-bromo-N,N-bis(tert-butoxycarbonyl)-3-(1-(2,5-difluorophenyl)ethoxy)pyridin-2-amine 
• 73183-34-3 bis(pinacol)diborane 
• 1979-36-8 2',5'-difluoroacetophenone 
• 1346818-36-7 5-bromo-3-(1-(2,5-difluorophenyl)ethoxy)pyridin-2-amine 
• 1346818-05-0 3-(1-(2,5-difluorophenyl)ethoxy)pyridin-2-amine 
• 1346817-88-6 3-(1-(2,5-difluorophenyl)ethoxy)-2-nitropyridine 
• 3874-31-5 (RS)-1-(2,5-difluorophenyl)ethanol 
• 2646-90-4 2,5-difluorobenzaldehyde 

Downstream Products

• 1613148-60-9 3-(6-(bis(tert-butoxycarbonyl)amino)-5-(1-(2,5-difluorophenyl)ethoxy)pyridin-3-yl)-6-(tert-butoxycarbonyl)-5,6,7,8-tetrahydro-1,6-naphthyridin-8-ol 
• 1613148-59-6 3-(6-amino-5-(1-(2,5-difluorophenyl)ethoxy)pyridin-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-8-ol 
• 1613148-58-5 N,N-bis(tert-butoxycarbonyl)-5-(5-(tert-butoxycarbonyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)-3-(1-(2,5-difluorophenyl)ethoxy)pyridin-2-amine 
• 1613148-55-2 3-(1-(2,5-difluorophenyl)ethoxy)-5-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)pyridin-2-amine 

Relevant articles and documents

Substituted pyridine compound and its method and use thereof

The invention relates to a novel substitutive pyridine compound, and a pharmaceutically acceptable salt and a pharmaceutical preparation of the substitutive pyridine compound for regulating the activity of protein kinases and regulating signal responses between cells or in the cells. Meanwhile, the invention further relates to a pharmaceutical composition containing the compound provided by the invention, and a method for treating high proliferative diseases of mammals, especially human with the pharmaceutical composition.

SUBSTITUTED CYCLIC COMPOUNDS AND METHODS OF USE

The present invention provides novel substituted alkynyl compounds, pharmaceutical acceptable salts and formulations thereof useful in modulating the protein tyrosine kinase activity, and in modulating cellular activities such as proliferation, differentiation, apoptosis, migration and invasion. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of hyperproliferative disorders in mammals, especially humans.