1614-98-8 Usage
Description
2-Propenoic acid, 3-(2-chlorophenyl)-2-methyl-, commonly known as 2-Methyl-3-(2-chlorophenyl)acrylic acid, is a chemical compound with the molecular formula C11H11ClO2. It is a derivative of acrylic acid that features a 2-chlorophenyl and a methyl group. This colorless to pale yellow liquid with a pungent odor is utilized in various chemical applications, including the production of pharmaceuticals, pesticides, and other chemicals. It also plays a role in the synthesis of organic compounds and as a reagent in chemical reactions. Due to its potential irritant properties, it should be handled and stored with caution.
Uses
Used in Pharmaceutical Industry:
2-Propenoic acid, 3-(2-chlorophenyl)-2-methylis used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with specific therapeutic properties.
Used in Pesticide Industry:
In the pesticide industry, 2-Propenoic acid, 3-(2-chlorophenyl)-2-methylis used as a key component in the formulation of various pesticides, leveraging its chemical structure to enhance the effectiveness of these products.
Used in Chemical Synthesis:
2-Propenoic acid, 3-(2-chlorophenyl)-2-methylis used as a building block in the synthesis of a range of organic compounds, contributing to the creation of new chemical entities with diverse applications.
Used as a Reagent in Chemical Reactions:
2-Propenoic acid, 3-(2-chlorophenyl)-2-methylserves as a reagent in various chemical reactions, facilitating specific transformations and processes that are essential in the production of different chemical products.
Check Digit Verification of cas no
The CAS Registry Mumber 1614-98-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,1 and 4 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1614-98:
(6*1)+(5*6)+(4*1)+(3*4)+(2*9)+(1*8)=78
78 % 10 = 8
So 1614-98-8 is a valid CAS Registry Number.
1614-98-8Relevant articles and documents
Highly efficient Rh-catalyzed asymmetric hydrogenation of α,β-unsaturated nitriles
Yan, Qiaozhi,Kong, Duanyang,Li, Meina,Hou, Guohua,Zi, Guofu
supporting information, p. 10177 - 10181 (2015/09/01)
A highly efficient enantioselective hydrogenation of α,β-unsaturated nitriles catalyzed by Rh-(R,R)-f-spiroPhos complex has been developed. With Rh-(R,R)-f-spiroPhos catalyst and under mild conditions, a wide range of α,β-unsaturated nitriles including the (E)- and (Z)-isomers of 3-alkyl-3-aryl, 3,3-diaryl, and 3,3-dialkyl α,β-unsaturated nitriles were hydrogenated to the corresponding chiral nitriles with excellent enantioselectivities (up to 99.9% ee) and high turnover numbers (TON up to 10,000).
Synthetic applications of Baylis-Hillman chemistry: An efficient and solely stereoselective synthesis of (E)-α-methylcinnamic acids and potent hypolipidemic agent LK-903 from unmodified Baylis-Hillman adducts
Das, Biswanath,Banerjee, Joydeep,Chowdhury, Nikhil,Majhi, Anjoy
, p. 1725 - 1727 (2007/10/03)
An efficient and solely stereoselective synthesis of (E)-α- methylcinnamic acids has been accomplished in single pot by reduction of the unmodified Baylis-Hillman adducts, methyl-3-hydroxy-3-aryl-2- methylenepropanoates with I2/NaBH4 reagent system at room temperature followed by hydrolysis. The efficacy of this method has been proved in the total synthesis of 1-[p-(myristyloxy)-α-methylcinnamoyl]glycerol, LK-903, a highly active hypolipidemic agent.
