161402-83-1Relevant articles and documents
SYNTHESIS OF 2,3,5,6-TETRAHYDROIMIDAZOTHIAZOLES
Kaugars, Girts,Martin, Scott E.,Nelson, Stephen J.,Watt, William
, p. 2593 - 2604 (1994)
The reactions of 2-amino-2-thiazoline with alkylating and acylating agents give initial reaction on the endocyclic nitrogen.Acyl groups, however, readily rearrange to the exocyclic nitrogen to give the products usually observed in these reactions.These observations clear up a considerable amount of confusion in the literature and lead to the efficient synthesis of 2,3,5,6-tetrahydroimidazothiazoles.