161452-19-3Relevant academic research and scientific papers
Analogs of biologically active, naturally occurring polyamines, pharmaceutical compositions and methods of treatment
-
Sheet 7, (2010/01/30)
Polyamines having the formula: or a salt thereof with a pharmaceutically acceptable acid wherein: R1-R6may be the same or different and are alkyl, aryl, aryl alkyl, cycloalkyl, optionally having an alkyl chain interrupted by at least
Antiproliferative Properties of Polyamine Analogues: A Structure-Activity Study
Bergeron, Raymond J.,McManis, James S.,Liu, Charles Z.,Feng, Yang,Weimar, William R.,et al.
, p. 3464 - 3476 (2007/10/02)
A basis set of polyamine analogues was designed and synthesized.These compounds were used to initiate a systematic investigation of the role of chain length, terminal nitrogen alkyl group size, and symmetry of the methylene backbone in the antineoplastic
