161455-97-6

Basic information

• Product Name: Acetamide, 2-bromo-N-(1-methylethyl)-N-phenyl-
• CAS NO: 161455-97-6
• Molecular Formula: C11H14BrNO
• Molecular Weight: 256.142
• Mol File: 161455-97-6.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Acetamide, 2-bromo-N-(1-methylethyl)-N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, 2-bromo-N-(1-methylethyl)-N-phenyl-(161455-97-6)
• EPA Substance Registry System: Acetamide, 2-bromo-N-(1-methylethyl)-N-phenyl-(161455-97-6)

Safety Data

• Hazardous Substances Data: 161455-97-6(Hazardous Substances Data)

Upstream product

• 1918-16-7 2-chloro-N-(1-methylethyl)-N-phenylacetamide 
• 768-52-5 N-Isopropylaniline 
• 598-21-0 2-Bromoacetyl bromide 

Downstream Products

• 161455-90-9 N-isopropyl-N-phenyl-2-(2-phenylamino-phenylamino)-acetamide 
• 173459-46-6 N-isopropyl-2-{2-oxo-5-phenyl-3-[(benzyloxycarbonyl)amino]-2,3-dihydro-benzo[e][1,4]diazepin-1-yl}-N-phenyl acetamide 
• 760922-81-4 2-(3-amino-2-oxo-5-phenyl-2,3-dihydro-benzo[e][1,4]diazepin-1-yl)-N-isopropyl-N-phenyl-acetamide 
• 179083-28-4 (R)-4-tert-Butoxycarbonylamino-4-{[(isopropyl-phenyl-carbamoyl)-methyl]-phenyl-carbamoyl}-butyric acid tert-butyl ester 
• 64788-47-2 N-isopropyl-1,3-dihydro-2H-indol-2-one 
• 10487-31-7 1-isopropyl-1H-indole-2,3-dione 
• 174180-73-5 2-(2-Aminophenylamino)-N-isopropyl-N-phenyl acetamide 
• 870615-64-8 2-(4-ethoxy-2-oxo-2,3-dihydro-benzo[b][1,4]diazepin-1-yl)-N-isopropyl-N-phenyl-acetamide 

Relevant articles and documents

Synthesis of Oxindole Derivatives via Intramolecular C–H Insertion of Diazoamides Using Ru(II)-Pheox Catalyst

This work presented the efficient intramolecular aromatic C–H insertion of diazoacetamide. The 1a–1o diazo compounds (except for 1k) were converted into their corresponding oxindoles via an intramolecular C–H insertion reaction in the presence of a Ru catalyst. The Ru-Pheox catalyst was shown to be highly efficient in this transformation in terms of the regioselectivity, producing the desired products in excellent yield (99%). The efficiency of the Ru catalyst reached 580 (TON) and 156 min?1 (TOF).

Tetraazabenzo[e]azulene derivatives and analogs thereof

This invention relates to CCK-A agonists of Formula (I) wherein R1-R4, A, B, X, D, E and G are as defined in the specificiation, as well as, among other things, pharmaceutical compositions containing the compounds and methods of use of the compounds and compositions. The compounds are useful in treating obesity.

METHOD OF INDUCING CHOLECYSTOKININ AGONIST ACTIVITY USING 1,4-BENZODIAZEPINE COMPOUNDS

A method of inducing a Cholescystokinin-A receptor agonist response in a mammal by administering a compound of formula (I), STR1 where R 1 is C 1-C 6 alkyl, C 3-6 cycloalkyl, phenyl, or substituted phenyl; R 2 is C 3-6 alkyl, C 3-6 cycloalkyl, C 3-6 alkenyl, benzyl, phenylC 1-3 alkyl or substituted phenyl; or NR 1 R 2 together form 1,2,3,4-tetrahydroquinoline or benzazepine mono-, di-, or trisubstituted independently with C 1-6 alkyl, C 1-6 alkoxy or halogen substituents; n is an integer selected from the grouping consisting of 0, 1,2 or 3; p is the integer 0 or 1; q is the integer 0 or 1; r is the integer 0 or 1, provided that when q is 0 then r is 0; R 3, R 4, R 5 and R 8 are selected from a variety of substituents; X is nitrogen, nitroso or R 8 ; m is an integer selected from the group consisting of 0, 1, 2 or 3; Y and Z are hydrogen or halogen, novel intermediates, a pharmaceutical composition for treating obesity, gall bladder stasis, disorders of pancreatic secretion, methods for such treatment and processes for preparing compounds of formula (I).