161497-17-2

Basic information

• Product Name: Methyl 4-((phenylsulfonyl)oxy)benzoate
• Synonyms: Methyl 4-((phenylsulfonyl)oxy)benzoate
• CAS NO: 161497-17-2
• Molecular Weight: 292.312
• Mol File: 161497-17-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Methyl 4-((phenylsulfonyl)oxy)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 4-((phenylsulfonyl)oxy)benzoate(161497-17-2)
• EPA Substance Registry System: Methyl 4-((phenylsulfonyl)oxy)benzoate(161497-17-2)

Safety Data

• Hazardous Substances Data: 161497-17-2(Hazardous Substances Data)

Upstream product

• 99-76-3 methyl 4-hydroxylbenzoate 
• 98-09-9 benzenesulfonyl chloride 

Downstream Products

• 63676-19-7 [6-methoxy-2-(4-methoxyphenyl)benzo[b]thiophen-3-yl](4-hydroxyphenyl)methanone 
• 1293362-49-8 benzenesulfonic acid-4-[6-methoxy-2-(4-methoxy-phenyl)-benzo[b]thiophene-3-carbonyl]-phenyl ester 
• 1293362-39-6 Sodium 4-[6-methoxy-2-(4-methoxy-phenyl)-benzo[b]thiophene-3-carbonyl]-phenolate 
• 1293362-40-9 Potassium 4-[6-methoxy-2-(4-methoxy-phenyl)-benzo[b]thiophene-3-carbonyl]-phenolate 
• 7507-41-7 4-benzenesulfonyloxy-benzoic acid 
• 720-75-2 methyl 4-phenylbenzoate 
• 792-74-5 4,4'-biphenyldicarboxylic acid dimethyl ester 

Relevant articles and documents

A process for preparing benzo[b]thiophene derivatives

The present invention relates in general to the field of organic chemistry, and in particular to the preparation of benzo[b]thiophene derivatives. These benzo[b]thiophene derivatives are useful as intermediates in the synthesis of pharmaceutically active agents such as raloxifene or derivatives thereof.

Aryl Mesylates in Metal-Catalyzed Homocoupling and Cross-Coupling Reactions. 1. Functional Symmetrical Biaryls from Phenols via Nickel-Catalyzed Homocoupling of Their Mesylates

Aryl sulfonates including mesylate derived from phenols are converted in high yields to biaryls by homocoupling in the presence of catalytic amounts of zero-valent nickel catalysts generated in situ.This reaction provides the most convenient method for the synthesis of many functional symmetrical biaryls and was applied to the preparation of 2,2'-, 3,3'-, and 4,4'-disubstituted biphenyls and other biaryls.The influence of the electronic and steric effects of substituents attached in the ortho, meta, and para positions of aryl sulfonates and the nature of the sulfonate leaving group on the yield of homocoupled product as well as their influence on the extent of various side reactions were investigated.In addition, the influence of the effects of the polarity and dryness of solvent, halide ion source and concentration, and ratio of catalyst and ligand to aryl sulfonate are discussed.