16151-03-4

Basic information

• Product Name: 1,2,4-Oxadiazole, 3-(4-methylphenyl)-5-phenyl-
• CAS NO: 16151-03-4
• Molecular Formula: C15H12N2O
• Molecular Weight: 236.273
• Mol File: 16151-03-4.mol
• Article Data: 29

Chemical Properties

• CAS DataBase Reference: 1,2,4-Oxadiazole, 3-(4-methylphenyl)-5-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,4-Oxadiazole, 3-(4-methylphenyl)-5-phenyl-(16151-03-4)
• EPA Substance Registry System: 1,2,4-Oxadiazole, 3-(4-methylphenyl)-5-phenyl-(16151-03-4)

Safety Data

• Hazardous Substances Data: 16151-03-4(Hazardous Substances Data)

Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule. In this case, the compound has 16 carbon (C) atoms, 12 hydrogen (H) atoms, 2 nitrogen (N) atoms, and 1 oxygen (O) atom.
2. Heterocyclic compound

Explanation

A heterocyclic compound is a cyclic compound that contains atoms of at least two different elements, in this case, nitrogen and oxygen.
3. Five-membered ring structure

Explanation

The compound has a ring structure consisting of five atoms, which are part of the 1,2,4-oxadiazole core.
4. Potential application in medicinal chemistry

Explanation

The compound has been studied for its possible use in the development of new drugs due to its reported antimicrobial, antifungal, and anticancer properties.
5. Antimicrobial properties

Explanation

The compound has shown the ability to inhibit the growth of microorganisms, making it a potential candidate for use in the development of antimicrobial drugs.
6. Antifungal properties

Explanation

The compound has demonstrated the ability to inhibit the growth of fungi, which could be useful in the development of antifungal medications.
7. Anticancer properties

Explanation

The compound has shown potential in inhibiting the growth of cancer cells, making it a candidate for further research in the development of anticancer drugs.
8. Fluorescent probe

Explanation

The compound has been investigated for its potential use as a fluorescent probe, which can be used to detect biological molecules and metal ions.
9. Organic electronics

Explanation

The compound has been studied for its potential use in the field of organic electronics, which involves the use of organic materials in electronic devices.
10. Building block in synthesis

Explanation

The compound can be used as a starting material or building block in the synthesis of other biologically active compounds, expanding its potential applications in various fields.

Upstream product

• 52809-98-0 N-benzoyl-4-methylthiobenzamide 
• 41110-16-1 C₁₅H₁₄N₂O₂ 
• 55661-47-7 1-phenyl-1-(piperidin-1-yl)methanimine 
• 13820-14-9 4-methylbenzonitrile oxide 
• 98-88-4 benzoyl chloride 
• 2579-22-8 Phenylpropargyl aldehyde 
• 19227-13-5 p-toluamidoxime 
• 93-97-0 benzoic acid anhydride 
• 104-87-0 4-methyl-benzaldehyde 
• 100-46-9 benzylamine 
• 108-88-3 toluene 
• 618-31-5 benzylidene dibromide 
• 19227-13-5 (Z)-N'-hydroxy-4-methylbenzimidamide 
• 100-51-6 benzyl alcohol 

Downstream Products

• 72094-49-6 4-(5-phenyl-1,2,4-oxadiazol-3-yl)benzoic acid 
• 52577-07-8 4-(5-phenyl-[1,2,4]oxadiazol-3-yl)-benzaldehyde 
• 72093-52-8 3-{4-[2-chloro-4-(4,5-diphenyl-oxazol-2-yl)-trans-styryl]-phenyl}-5-phenyl-[1,2,4]oxadiazole 
• 72093-79-9 2-{3-chloro-4-[4-(5-phenyl-[1,2,4]oxadiazol-3-yl)-trans-styryl]-phenyl}-benzooxazole 
• 72093-57-3 5-methyl-2-{4-[4-(5-phenyl-[1,2,4]oxadiazol-3-yl)-trans-styryl]-phenyl}-benzooxazole 
• 72093-80-2 5-tert-butyl-2-{3-chloro-4-[4-(5-phenyl-[1,2,4]oxadiazol-3-yl)-trans-styryl]-phenyl}-benzooxazole 
• 72093-67-5 7-phenyl-2-{4-[4-(5-phenyl-[1,2,4]oxadiazol-3-yl)-trans-styryl]-phenyl}-benzooxazole 
• 72093-65-3 5-phenyl-2-{4-[4-(5-phenyl-[1,2,4]oxadiazol-3-yl)-trans-styryl]-phenyl}-benzooxazole 
• 72093-66-4 6-phenyl-2-{4-[4-(5-phenyl-[1,2,4]oxadiazol-3-yl)-trans-styryl]-phenyl}-benzooxazole 
• 72093-62-0 5-tert-butyl-2-{4-[4-(5-phenyl-[1,2,4]oxadiazol-3-yl)-trans-styryl]-phenyl}-benzooxazole 

Relevant articles and documents

Rapid and efficient synthesis of 1,2,4-oxadiazoles utilizing polymer-supported reagents under microwave heating

(Chemical Equation Presented) 1,2,4-Oxadiazoles can be rapidly and efficiently synthesized from a variety of readily available carboxylic acids and amidoximes using either method A or method B. The use of commercially available polymersupported reagents c

Convenient one-pot synthesis of 1,2,4-oxadiazoles and 2,4,6-triarylpyridines using graphene oxide (GO) as a metal-free catalyst: Importance of dual catalytic activity

A convenient and efficient process for the synthesis of 3,5-disubstituted 1,2,4-oxadiazoles and 2,4,6-triarylpyridines has been described using an inexpensive, environmentally benign, metal-free heterogeneous carbocatalyst, graphene oxide (GO). GO plays a dual role of an oxidizing agent and solid acid catalyst for synthesizing 1,2,4-oxadiazoles and triarylpyridines. This dual catalytic activity of GO is due to the presence of oxygenated functional groups which are distributed on the nanosheets of graphene oxide. A broad scope of substrate applicability and good sustainability is offered in this developed protocol. The results of a few control experiments reveal a plausible mechanism and the role of GO as a catalyst was confirmed by FTIR, XRD, SEM, and HR-TEM analysis.

Potassium Poly(Heptazine Imide): Transition Metal-Free Solid-State Triplet Sensitizer in Cascade Energy Transfer and [3+2]-cycloadditions

Polymeric carbon nitride materials have been used in numerous light-to-energy conversion applications ranging from photocatalysis to optoelectronics. For a new application and modelling, we first refined the crystal structure of potassium poly(heptazine imide) (K-PHI)—a benchmark carbon nitride material in photocatalysis—by means of X-ray powder diffraction and transmission electron microscopy. Using the crystal structure of K-PHI, periodic DFT calculations were performed to calculate the density-of-states (DOS) and localize intra band states (IBS). IBS were found to be responsible for the enhanced K-PHI absorption in the near IR region, to serve as electron traps, and to be useful in energy transfer reactions. Once excited with visible light, carbon nitrides, in addition to the direct recombination, can also undergo singlet–triplet intersystem crossing. We utilized the K-PHI centered triplet excited states to trigger a cascade of energy transfer reactions and, in turn, to sensitize, for example, singlet oxygen (1O2) as a starting point to synthesis up to 25 different N-rich heterocycles.