1616088-10-8

Basic information

• Product Name: N-[(E)-2-(3-ethoxy-3-oxoprop-1-en-1-yl)tetrafluorobenzoyl]-S-methyl-S-phenylsulfoximine
• CAS NO: 1616088-10-8
• Molecular Weight: 429.392
• Mol File: 1616088-10-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[(E)-2-(3-ethoxy-3-oxoprop-1-en-1-yl)tetrafluorobenzoyl]-S-methyl-S-phenylsulfoximine(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(E)-2-(3-ethoxy-3-oxoprop-1-en-1-yl)tetrafluorobenzoyl]-S-methyl-S-phenylsulfoximine(1616088-10-8)
• EPA Substance Registry System: N-[(E)-2-(3-ethoxy-3-oxoprop-1-en-1-yl)tetrafluorobenzoyl]-S-methyl-S-phenylsulfoximine(1616088-10-8)

Safety Data

• Hazardous Substances Data: 1616088-10-8(Hazardous Substances Data)

Upstream product

• 1616087-92-3 N-[2,3,4,5-tetrafluorobenzoyl]-S-methyl-S-phenylsulfoximine 
• 140-88-5 ethyl acrylate 
• 1193-82-4 racemic methyl phenyl sulfoxide 
• 4381-25-3 S-methyl-S-phenylsulfoximine 

Relevant articles and documents

Sulfoximine-directed ruthenium-catalyzed ortho -C-H Alkenylation of (Hetero)Arenes: Synthesis of EP3 receptor antagonist analogue

The reusable sulfoximine directing-group-assisted Ru(II)-catalyzed chemo- and regioselective ortho-C-H alkenylation of arenes and heteroarenes with acrylates and α,β-unsaturated ketones/vinyl sulfone is shown. The N-aroyl sulfoximine undergoes annulation with diphenylacetylene, delivering isoquinolinones and methyl phenyl sulfoxide. The present protocol is successfully employed for the synthesis of the EP3 receptor antagonist analogue.