1616410-47-9Relevant academic research and scientific papers
Dicapryloyl diisothiocyanate derivative and preparing method and application thereof
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, (2016/12/22)
The invention provides a dicapryloyl diisothiocyanate derivative and a preparing method and application thereof.The molecular structure of the dicapryloyl diisothiocyanate derivative contains a great number of lipophilic groups such as thioacid amide, thiourea and thioamide ester and carboxyl hydrophilic groups.The preparing method includes the steps that diacyl chloride and thiocyanate are subjected to a substitution reaction to generate the intermediate product dicapryloyl diisothiocyanate, and the intermediate product and an alcohol, amine, mercaptan or phenolic compound are subjected to an addition reaction to generate the dicapryloyl diisothiocyanate derivative.The preparing method is simple, the prepared dicapryloyl diisothiocyanate derivative serving as a non-molybdenum sulfide ore inhibitor applied to flotation separation of sulfuration molybdenum ore and non-molybdenum sulfide ore, the sulfuration molybdenum ore can be effectively separated from copper sulfide ore, galena, sphalerite, iron pyrite bismuth sulphide ore, and the grade of molybdenum concentrate is improved.
Bis-Thiourea bearing aryl and amino acids side chains and their antibacterial activities
Wan Zullkiplee, Wan Sharifatun Handayani,Abd Halim, Ainaa Nadiah,Ngaini, Zainab,Mohd Ariff, Maya Asyikin,Hussain, Hasnain
, p. 832 - 838 (2014/07/08)
(Equation present) A series of symmetrical 1,3-bis thiourea 1a-e and 1,4-bis thiourea derivatives 2a-e have been successfully synthesized from the reactions of amines with 3-acetylbenzoyl isothiocyanate and 4-acetylbenzoyl isothiocyanate, respectively. All the synthesized compounds were characterized by FT-IR spectroscopy and 1H and 13C NMR spectroscopy. The compounds were screened for their antibacterial activity by turbidimetric method using gram-negative bacteria (E. coli ATCC 8739) using turbidimetric method. The newly synthesized bis-thiourea derivatives bearing aryl side chains showed good antibacterial activity against E. coli. The effect of the molecular structure of the synthesized compounds on the antibacterial activity is discussed. 2014 Copyright Taylor & Francis Group, LLC.
