1617508-99-2Relevant academic research and scientific papers
Carbonic anhydrase inhibitors. Synthesis of a novel series of 5-substituted 2,4-dichlorobenzenesulfonamides and their inhibition of human cytosolic isozymes i and II and the transmembrane tumor-associated isozymes IX and XII
S?awiński, Jaros?aw,Pogorzelska, Aneta,Zo?nowska, Beata,Brozewicz, Kamil,Vullo, Daniela,Supuran, Claudiu T.
, p. 47 - 55 (2014/06/10)
A series of novel 5-substituted 2,4-dichlorobenzenesulfonamides 5a-c, 6a-d, 7a-j and 10a-i have been synthesized and investigated as inhibitors of four isoforms of zinc enzyme carbonic anhydrase (CA.EC 4.2.1.1), that is the cytosolic CA I and II, and tumo
