5046-15-1Relevant academic research and scientific papers
SELECTIVE INHIBITORS OF CARBONIC ANHYDRASE
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Page/Page column 27, (2017/02/24)
Invention is related to novel compounds – benzenesulfonamides of general formulas (I) and (II). The compounds can be used in biomedicine as active ingredients in pharmaceutical formulations, because they inhibit enzymes which participate in disease progre
Carbonic anhydrase inhibitors. Synthesis of a novel series of 5-substituted 2,4-dichlorobenzenesulfonamides and their inhibition of human cytosolic isozymes i and II and the transmembrane tumor-associated isozymes IX and XII
S?awiński, Jaros?aw,Pogorzelska, Aneta,Zo?nowska, Beata,Brozewicz, Kamil,Vullo, Daniela,Supuran, Claudiu T.
, p. 47 - 55 (2014/06/10)
A series of novel 5-substituted 2,4-dichlorobenzenesulfonamides 5a-c, 6a-d, 7a-j and 10a-i have been synthesized and investigated as inhibitors of four isoforms of zinc enzyme carbonic anhydrase (CA.EC 4.2.1.1), that is the cytosolic CA I and II, and tumo
