16180-26-0

Basic information

• Product Name: (2R)-2-[(5alpha,18R)-3,6-dimethoxy-17-methyl-7,8-didehydro-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-18-yl]pentan-2-ol
• CAS NO: 16180-26-0
• Molecular Formula: C₂₆H₃₅NO₄
• Molecular Weight: 425.5604
• Mol File: 16180-26-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 543.3°C at 760 mmHg
• Flash Point: 282.4°C
• Density: 1.25g/cm³
• Vapor Pressure: 1.23E-12mmHg at 25°C
• Refractive Index: 1.621
• CAS DataBase Reference: (2R)-2-[(5alpha,18R)-3,6-dimethoxy-17-methyl-7,8-didehydro-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-18-yl]pentan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-2-[(5alpha,18R)-3,6-dimethoxy-17-methyl-7,8-didehydro-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-18-yl]pentan-2-ol(16180-26-0)
• EPA Substance Registry System: (2R)-2-[(5alpha,18R)-3,6-dimethoxy-17-methyl-7,8-didehydro-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-18-yl]pentan-2-ol(16180-26-0)

Safety Data

• Hazardous Substances Data: 16180-26-0(Hazardous Substances Data)

Upstream product

• 76-57-3 codeine 
• 106-94-5 propyl bromide 
• 15358-22-2 thevinone 
• 60342-45-2 N-(ethoxycarbonyl)norcodeinone 
• 36397-12-3 N-desmethyl-N-carboethoxycodeine 
• 757950-17-7 N-carboethoxythebaine 
• 115-37-7 thebaine 
• 107-08-4 1-iodo-propane 
• 10557-57-0 propylmagnesium iodide 
• 927-77-5 n-propylmagnesium bromide 

Downstream Products

• 92264-44-3 S-etorphine 
• 25333-77-1 3-acetoxy-4,5α-epoxy-19anti-((R)-1-hydroxy-1-methyl-butyl)-6-methoxy-17-methyl-6β,14-ethano-morphin-7-ene 
• 14521-96-1 etorphine 

Relevant articles and documents

A facile synthesis and structural verification of etorphine and dihydroetorphine from codeine

In this study, an improved process for the synthesis of etorphine and dihydroetorphine from codeine with an overall yield of 2.7% and 1.5% respectively is described. The structure of 19-propylthevinol 7 was verfied by X-ray structure analysis. This result is promising for synthesizing various morphine-based drugs.

Novel analgesics and molecular rearrangements in the morphine-thebaine group. II. Alcohols derived from 6,14-endo-etheno- and 6,14-endo-ethanotetrahydrothebaine.

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