161807-50-7

Upstream product

• 39806-16-1 ethyl (2E,4E)-5-phenyl-penta-2,4-dienoate 

Downstream Products

• 326603-41-2 ethyl (E)-3-[(4R,5R)-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-yl]prop-2-enoate 
• 371978-07-3 {(2S,3R)-3-[(4R,5R)-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-yl]oxiran-2-yl}methanol 
• 371978-06-2 (E)-3-[(4R,5R)-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-yl]prop-2-en-1-ol 
• 934666-67-8 (1R)-1-[(4R,5R)-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-yl]propane-1,3-diol 
• 934666-69-0 methyl (Z,5R)-5-[(4R,5R)-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-yl]-5-hydroxypent-2-enoate 
• 934666-68-9 (3R)-3-[(4R,5R)-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-yl]-3-hydroxypropanal 

Relevant academic research and scientific papers

A simple and efficient total synthesis of a styryllactone, 7-epi-goniodiol

Regioselective mono-dihydroxylation, Red-Al reduction, and cis-Horner-Wadsworth-Emmons reactions have been efficiently performed as key steps in the synthesis of 7-epi-goniodiol, isolated from Goniothalamus leiocarpus. Georg Thieme Verlag Stuttgart.

Remote steric effect on the regioselectivity of Sharpless asymmetric dihydroxylation

Studies on the regioselectivities for the Sharpless asymmetric dihydroxylation (AD) of conjugated dienoates, trienoates, dienones and dienamides are described. Excellent regioselectivities were obtained in straight chain dienoates, all trienoates, ketones

Efficient and versatile stereoselective synthesis of cryptophycins

The cryptophycins are a family of cyclic depsipeptides with four retrosynthetic units A to D which correspond to the respective amino acids and hydroxy acids. A new synthetic route to unit A allows the selective generation of all four stereogenic centres

Selective Asymmetric Dihyroxylation of Polyenes

The asymmetric dihydroxylation procedure (AD) is applied to a variety of polyenes.In many cases excellent regioselectivities are obtained.The observed selectivities are rationalized in terms of electronic and/or steric inherent to the substrate, superimposed on the substrate's favorable or unfavorable interactions with the binding pocket of the AD ligand.Surprisingly, for medium and large ring olefins with trans-double bonds outstanding enantioselectivities are realized using the pyrimidine ligands.A hexaol of D3 symmetry is prepared from all trans cyclodecatriene.