161821-89-2

Upstream product

• 65-71-4 2,4-dihydroxy-5-methylpyrimidine 
• 161822-02-2 1,2-di-O-acetyl-3-deoxy-3-C-dimethylphosphono-5-O-benzoyl-α-D-ribofuranose 

Downstream Products

• 161821-86-9 N1-(2,3-dideoxy-3-(S)-C-dimethylphosphono-5-O-benzoyl-β-D-ribofuranosyl)-thymine 
• 161821-95-0 N1-(3-deoxy-3-C-dimethylphosphono-5-O-benzoyl-β-D-ribofuranosyl)-thymine 

Relevant academic research and scientific papers

3'-C-Phosphonates as Nucleotides Analogues Synthesis Starting from Original C-Phosphonosugars (in ribo- and deoxyribo- series)

3-C-phosphonosugars were synthetised starting from 2-deoxy-D-ribose and α-D-xylofuranose via the Pudovic rection followed by reduction.Their condensation with nucleobases (thymine and adenine) gave original 3'-C-phosphononucleosides in ribo- and 2-deoxyribo- series, with a stereocontrol of the reactions.Key words: 3-C-phosphonosugar, 3'-C-phosphononucleoside, Pudovic reaction, α-hydroxyphosphonate