16183-19-0Relevant academic research and scientific papers
Room-temperature chromium(II)-catalyzed direct arylation of pyridines, aryl oxazolines, and imines using arylmagnesium reagents
Kuzmina, Olesya M.,Knochel, Paul
, p. 5208 - 5211 (2014)
We report a CrCl2-catalyzed oxidative arylation of various pyridines, aryl oxazolines, and aryl imines using aromatic Grignard reagents in the presence of 2,3-dichlorobutane (DCB). Most of the reactions proceed rapidly at 25 °C and do not requi
The synthesis of α-aryl-α-aminophosphonates and α-aryl-α-aminophosphine oxides by the microwave-assisted Pudovik reaction
Bálint, Erika,Tajti, ádám,ádám, Anna,Csontos, István,Karaghiosoff, Konstantin,Czugler, Mátyás,ábrányi-Balogh, Péter,Keglevich, Gy?rgy
supporting information, p. 76 - 86 (2017/02/15)
A family of α-aryl-α-aminophosphonates and α-aryl-α-aminophosphine oxides was synthesized by the microwave-assisted solvent-free addition of dialkyl phosphites and diphenylphosphine oxide, respectively, to imines formed from benzaldehyde derivatives and primary amines. After optimization, the reactivity was mapped, and the fine mechanism was evaluated by DFT calculations. Two α-aminophosphonates were subjected to an X-ray study revealing a racemic dimer formation made through a N-H?O=P intermolecular hydrogen bridges pair.
