16183-39-4 Usage
Uses
Used in Pharmaceutical Industry:
CHEMBRDG-BB 4024926 is used as a potential histone deacetylase (HDAC) inhibitor for its capacity to modulate gene expression. This application is significant in cancer therapy, where the compound may contribute to the regulation of genes associated with the development and progression of cancerous cells.
Used in Cancer Therapy Research:
In the field of oncology, CHEMBRDG-BB 4024926 is utilized as a lead compound for investigating its potential to treat cancer. Its role as an HDAC inhibitor suggests that it may have the ability to target and alter the behavior of cancer cells, offering a new avenue for therapeutic intervention.
Used in Drug Development:
CHEMBRDG-BB 4024926 serves as a starting point for drug development efforts, given its potential biological activity and structure. Researchers and pharmaceutical companies may use CHEMBRDG-BB 4024926 to design and synthesize new drugs that can effectively target HDACs, leading to advancements in the treatment of various diseases, including cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 16183-39-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,1,8 and 3 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 16183-39:
(7*1)+(6*6)+(5*1)+(4*8)+(3*3)+(2*3)+(1*9)=104
104 % 10 = 4
So 16183-39-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H16ClN/c1-2-3-8-13-9-10-6-4-5-7-11(10)12/h4-7,13H,2-3,8-9H2,1H3
16183-39-4Relevant academic research and scientific papers
Reductive Amination Revisited: Reduction of Aldimines with Trichlorosilane Catalyzed by Dimethylformamide─Functional Group Tolerance, Scope, and Limitations
Campbell, Joanna L. P.,Davies, Christopher D.,Ho?ek, Jan,Ko?ovsky, Pavel,Kysilka, Ond?ej,Popov, Kirill K.,Pour, Milan
, p. 920 - 943 (2022/01/27)
Aldimines, generated in situ from aliphatic, aromatic, and heteroaromatic aldehydes and aliphatic, aromatic, and heteroaromatic primary or secondary amines, can be reduced with trichlorosilane in the presence of dimethylformamide (DMF) as an organocatalys
Effect of the temperature on the stoichiometry of borane dimethyl sulfide reduction of secondary and tertiary amides
Bonnat,Hercouet,Le Corre
, p. 1579 - 1582 (2007/10/02)
A simple procedure has been described for the reduction of secondary and tertiary amides to amines using borane-dimethyl sulfide in theoretical amounts.
Antiatherosclerotic ureas and thioureas
-
, (2008/06/13)
This invention is concerned with ureas and thioureas which may be represented by the formula: STR1 wherein X represents at least one substituent selected from the group consisting of (C1 -C4)alkyl, (C1 -C4)alken
