62797-97-1

Usage

Uses

Used in Pharmaceutical Research and Development:
N-n-Butyl-2-chlorobenzamide, 97% is used as a building block for the synthesis of new pharmaceutical compounds, contributing to the development of innovative drugs with potential therapeutic applications.
Used in Agrochemical Production:
In the agrochemical industry, N-n-Butyl-2-chlorobenzamide, 97% is used as an intermediate in the production of various agrochemicals, such as pesticides and herbicides, to enhance crop protection and yield.
Used in Dye Manufacturing:
This chemical compound is utilized as an intermediate in the manufacturing process of dyes, contributing to the creation of a wide range of colorants used in various industries, including textiles, plastics, and printing.
Used in Laboratory Experiments and Chemical Reactions:
N-n-Butyl-2-chlorobenzamide, 97% is employed as a reagent in laboratory settings, facilitating various chemical reactions and experiments, thus aiding in scientific research and discovery.
Storage and Safety:
N-n-Butyl-2-chlorobenzamide, 97% should be stored in a cool, dry, and well-ventilated area, away from incompatible substances to ensure its stability and safety. When handling this chemical, it is crucial to follow safety precautions and wear appropriate protective equipment to prevent exposure and potential hazards.

InChI:InChI=1/C11H14ClNO/c1-2-3-8-13-11(14)9-6-4-5-7-10(9)12/h4-7H,2-3,8H2,1H3,(H,13,14)

Upstream product

• 109-73-9 N-butylamine 
• 118-91-2 ortho-chlorobenzoic acid 
• 95-49-8 2-methylchlorobenzene 
• 609-65-4 o-chlorobenzoyl chloride 
• 89-98-5 2-chloro-benzaldehyde 

Downstream Products

• 66897-47-0 N-Butyl-N-(2-chloro-benzoyl)-benzenesulfonamide 
• 4299-07-4 2-butyl-1,2-benzothiazolin-3-one 
• 1384754-91-9 trans-[(C₆H₄C(O)NH-n-Bu)Ni(II)(trimethylphosphine)2Cl] 
• 16183-39-4 N-(2′-chlorobenzyl)-1-butylamine 
• 16183-40-7 butyl-(2-chloro-benzyl)-amine; hydrochloride 

Relevant academic research and scientific papers

Radical-mediated divergent cyclization of benzamides toward perfluorinated or cyanated isoquinolinediones

A simple and efficient copper-controlled divergent cyclization of benzamides, which leads to perfluorinated or cyanated isoquinolinediones, is developed. In the presence of AIBN, methacryloyl benzamides with perfluoroalkyl iodides undergo cascade radical addition/cyclization to afford perfluoroinated isoquinolinediones as the major product under metal-free conditions, whereas the use of CuI (10 mol%) is able to redirect the cyclization to yield isoquinolinediones bearing an α-cyano quaternary carbon center. The cyclization features controllable divergent synthesis and a broad substrate scope as well as highly practical reaction conditions, thereby making this strategy a highly attractive means to fluorinate or cyanate isoquinolinediones.

In situ protection and deprotection of amines for iron catalyzed oxidative amidation of aldehydes

An environmentally friendly synthetic route by the application of CO2 to synthesize amides via in situ protection and deprotection of amines for iron catalyzed oxidative amidation of aldehydes was developed. Various secondary and tertiary amides have been synthesized in moderate to good yields under mild and neutral reaction conditions. The use of amine hydrochloride salts and hence base for neutralization step is totally avoided in this protocol.

Direct oxidative amidation between methylarenes and amines in water

An environmentally friendly direct oxidative amidation between methylarenes and free amines was developed. The aromatic amide could be prepared efficiently from raw chemicals by employing TBHP as a "green" oxidant with co-catalysis of TBAI and FeCl3 in water.

Formal nucleophilic substitution of bromocyclopropanes with amides en route to conformationally constrained β-amino acid derivatives

A chemo- and diastereoselective protocol for the formal nucleophilic substitution of 2-bromocyclopropylcarboxamides with secondary amides is described. This method allows for convergent and highly selective synthesis of trans-β-aminocyclopropane carboxylic acid derivatives.