161830-29-1

Basic information

• Product Name: 6-nitro-7-chloro-4-(3-methylanilino)quinazoline
• Synonyms: 6-nitro-7-chloro-4-(3-methylanilino)quinazoline
• CAS NO: 161830-29-1
• Molecular Weight: 314.731
• Mol File: 161830-29-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 6-nitro-7-chloro-4-(3-methylanilino)quinazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 6-nitro-7-chloro-4-(3-methylanilino)quinazoline(161830-29-1)
• EPA Substance Registry System: 6-nitro-7-chloro-4-(3-methylanilino)quinazoline(161830-29-1)

Safety Data

• Hazardous Substances Data: 161830-29-1(Hazardous Substances Data)

Upstream product

• 31374-18-2 7-chloroquinazolin-4(1H)-one 
• 7664-93-9 sulfuric acid 
• 108-44-1 1-amino-3-methylbenzene 
• 162012-71-7 4,7-dichloro-6-nitro-quinazoline 
• 53449-14-2 7-chloro-6-nitro-4(3H)-quinazolinone 
• 31374-18-2 7-chloro-3,4-dihydroquinazolin-4-one 
• 89-77-0 2-Amino-4-chlorobenzoic acid 

Downstream Products

• 153437-17-3 6-amino-7-methoxy-4-(3'-methylanilino)quinazoline 
• 31374-18-2 7-chloroquinazolin-4(1H)-one 

Relevant articles and documents

Phenyl [...] compound and its preparation method, pharmaceutical composition, drug use (by machine translation)

The invention provides a phenylurea coupling quinazoline compound or a pharmaceutically acceptable salt thereof represented by formula (I), wherein R1 represents H, represents Br, Cl or F, represents -CH3, -CH2-CH3, -CH2(CH3)2 or -CF3, represents -O-CH3, -O-CH2-CH3 or -O-CH2(CH3)2, or represents -C[triple bond]CH or -C[triple bond]N; n1 is 1, 2, 3, 4 or 5; one of R2 and R3 is a group represented by formula (II); R4 represents H, represents Br, Cl or F, represents -CH3, -CH2-CH3, -CH2(CH3)2 or -CF3, represents -O-CH3, -O-CH2-CH3 or -O-CH2(CH3)2, represents -NH2, or represents -NO2; n2 is 1, 2, 3, 4 or 5; and the other one of R2 and R3 represents H, -O-CH3, -O-CH2-CH3, -O-CH2(CH3)2, or the following groups.

QUINAZOLINE DERIVATIVES USEFUL FOR TREATMENT OF NEOPLASTIC DISEASE

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