161855-69-2Relevant articles and documents
The perfect penicillin? Inhibition of a bacterial DD-peptidase by peptidoglycan-mimetic β-lactams
Josephine, Helen R.,Kumar, Ish,Pratt
, p. 8122 - 8123 (2007/10/03)
6-(Glycyl-L-α-aminopimelyl)-aminopenicillanic acid and 7-(glycyl-L-α-aminopimelyl)-aminocephalosporanic acid have been synthesized as Streptomyces sp. peptidoglycan-mimetic β-lactams. These compounds inactivate the Streptomyces R61 DD-peptidase with rate
2-thiosubstituted carbapenems
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, (2008/06/13)
Carbapenem antibiotic compounds of the general formula: STR1 wherein the moiety STR2 is a 4, 5 or 6 membered mono, di- or tri- substituted oxygen or sulfur containing ring; wherein Z is oxygen, sulfur, sulfoxide and sulfone, pharmaceutical compositions thereof useful for the treatment of bacterial infections, processes for preparing the compounds and new intermediates useful in the process.