1618648-60-4
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Basic information
- Product Name: 2,2,2,-trifluoro-N-[2-(methylsulphonyl)ethyl]-N-({5-[4-(tetrahydro-2H-pyran-2-yloxy)quinazolin-6-yl]furan-2-yl}methyl) acetamide
- Synonyms: 2,2,2,-trifluoro-N-[2-(methylsulphonyl)ethyl]-N-({5-[4-(tetrahydro-2H-pyran-2-yloxy)quinazolin-6-yl]furan-2-yl}methyl) acetamide
- CAS NO:1618648-60-4
- Molecular Formula:
- Molecular Weight: 527.521
- EINECS: N/A
- Product Categories: N/A
- Mol File: 1618648-60-4.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 2,2,2,-trifluoro-N-[2-(methylsulphonyl)ethyl]-N-({5-[4-(tetrahydro-2H-pyran-2-yloxy)quinazolin-6-yl]furan-2-yl}methyl) acetamide(CAS DataBase Reference)
- NIST Chemistry Reference: 2,2,2,-trifluoro-N-[2-(methylsulphonyl)ethyl]-N-({5-[4-(tetrahydro-2H-pyran-2-yloxy)quinazolin-6-yl]furan-2-yl}methyl) acetamide(1618648-60-4)
- EPA Substance Registry System: 2,2,2,-trifluoro-N-[2-(methylsulphonyl)ethyl]-N-({5-[4-(tetrahydro-2H-pyran-2-yloxy)quinazolin-6-yl]furan-2-yl}methyl) acetamide(1618648-60-4)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1618648-60-4(Hazardous Substances Data)
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Molecular structure
The compound consists of a fluorinated acetamide group, a methylsulphonylethylamine group, and a furan ring connected to a quinazoline group.Target
The compound is a dual inhibitor of spleen tyrosine kinase (SYK) and FMS-like tyrosine kinase 3 (FLT3)Activity
TAK-659 exhibits anti-inflammatory and anti-cancer activities.Mechanism of action
The compound targets SYK and FLT3 kinases, which play crucial roles in regulating immune responses and cancer cell proliferation.Preclinical studies
TAK-659 has shown promising results in preclinical studies, demonstrating its potential as a therapeutic agent.Investigational applications
The compound is currently being investigated for its potential use in treating various inflammatory and neoplastic diseases.Check Digit Verification of cas no
The CAS Registry Mumber 1618648-60-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,1,8,6,4 and 8 respectively; the second part has 2 digits, 6 and 0 respectively.Calculate Digit Verification of CAS Registry Number 1618648-60:
(9*1)+(8*6)+(7*1)+(6*8)+(5*6)+(4*4)+(3*8)+(2*6)+(1*0)=194
194 % 10 = 4
So 1618648-60-4 is a valid CAS Registry Number.
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2,2,2,-trifluoro-N-[2-(methylsulphonyl)ethyl]-N-({5-[4-(tetrahydro-2H-pyran-2-yloxy)quinazolin-6-yl]furan-2-yl}methyl) acetamide
