161924-01-2

Basic information

• Product Name: 3'-O-(carboxymethyl)-5'-O-(4,4'-dimethoxytrityl)thymidine
• CAS NO: 161924-01-2
• Molecular Weight: 602.641
• Mol File: 161924-01-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3'-O-(carboxymethyl)-5'-O-(4,4'-dimethoxytrityl)thymidine(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-O-(carboxymethyl)-5'-O-(4,4'-dimethoxytrityl)thymidine(161924-01-2)
• EPA Substance Registry System: 3'-O-(carboxymethyl)-5'-O-(4,4'-dimethoxytrityl)thymidine(161924-01-2)

Safety Data

• Hazardous Substances Data: 161924-01-2(Hazardous Substances Data)

Upstream product

• 50-89-5 thymidine 
• 40615-39-2 5'-O-(4-4'-dimethoxytrityl)thymidine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 121310-51-8 5'-O-(4,4'-dimethoxytrityl)-3'-O-(methoxycarbonylmethyl)thymidine 
• 929075-68-3 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-(2-oxoethyl)thymidine 
• 3926-62-3 sodium monochloroacetic acid 

Downstream Products

• 1385787-00-7 3'-O-(N-carbonylmethyl)-5'-O-(4,4'-dimethoxytrityl)thymidylyl-(3'->5')-5'-O-amino-3'-O-(tert-butyldimethylsilyl)thymidine 
• 121310-51-8 5'-O-(4,4'-dimethoxytrityl)-3'-O-(methoxycarbonylmethyl)thymidine 

Relevant articles and documents

Synthesis of thymidine dimers from 5′-O-aminothymidine

The synthesis of modified oligonucleotides is of great importance for various therapeutic and diagnostic applications. The facile secondary structure formation of N-oxyamide-linked peptide analogues and the high nucleophilicity of the aminooxy function prompted us to prepare O-amino nucleoside derived dinucleosides. Herein, the efficient synthesis of three novel thymidine dimers with N-oxyamide, oxime and oxyamine linkages via a convergent approach from a common 5-O-aminothymidine is reported. Georg Thieme Verlag Stuttgart · New York.