929075-68-3

Upstream product

• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 40615-39-2 5'-O-(4-4'-dimethoxytrityl)thymidine 
• 50-89-5 thymidine 
• 929075-67-2 C₃₄H₃₈N₂O₉ 

Downstream Products

• 929075-74-1 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-dephosphinicothymidylyl(6,9-dioxa-3,12-diazatetradecane-1,14-diyl)-(3'-5')-3'-O-[(tert-butyl)dimethylsilyl]thymidine 
• 1385787-00-7 3'-O-(N-carbonylmethyl)-5'-O-(4,4'-dimethoxytrityl)thymidylyl-(3'->5')-5'-O-amino-3'-O-(tert-butyldimethylsilyl)thymidine 
• 161924-01-2 3'-O-(carboxymethyl)-5'-O-(4,4'-dimethoxytrityl)thymidine 
• 1385787-05-2 C₄₉H₆₁N₅O₁₂Si 
• 1385787-01-8 C₄₉H₆₁N₅O₁₂Si 
• 1572186-15-2 C₃₇H₄₅N₂O₁₀P 

Relevant academic research and scientific papers

Synthesis, characterization and anti-cancer activity of a peptide nucleolipid bioconjugate

The synthesis, characterization and anti-cancer activity of a novel peptide nucleolipid bioconjugate is reported in this study. The prerequisite 5′-carboxy derived nucleolipid was synthesized following a five-step solution-phase approach and then coupled

Inhibition of human thymidine phosphorylase by conformationally constrained pyrimidine nucleoside phosphonic acids and their "open-structure" isosteres

A series of conformationally constrained uridine-based nucleoside phosphonic acids containing annealed 1,3-dioxolane and 1,4-dioxane rings and their "open-structure" isosteres were synthesized and evaluated as potential multisubstrate-like inhibitors of t

Synthesis of thymidine dimers from 5′-O-aminothymidine

The synthesis of modified oligonucleotides is of great importance for various therapeutic and diagnostic applications. The facile secondary structure formation of N-oxyamide-linked peptide analogues and the high nucleophilicity of the aminooxy function prompted us to prepare O-amino nucleoside derived dinucleosides. Herein, the efficient synthesis of three novel thymidine dimers with N-oxyamide, oxime and oxyamine linkages via a convergent approach from a common 5-O-aminothymidine is reported. Georg Thieme Verlag Stuttgart · New York.

Synthesis and hybridization properties of oligodeoxynucleotides with long-chain linkers

New oligonucleotides with a long-chain linker (6,9-dioxa-3,12- diazatetradecane-1,14-diyl) in their backbone were synthesized, and their hybridization properties were studied by measurement of their Tm curves and fluorescence spectra. The Tsub