16196-83-1Relevant academic research and scientific papers
Synthesis of N-substituted 7β-diprenorphine derivatives
Marton,Miklos,Hosztafi,Makleit
, p. 829 - 848 (1995)
The separation of thevinone (2a) and β-thevinone (2b), as well as that of dihydrothevinone (3a) and β-dihydrothevinone (3b) was accomplished. By the application of various procedures numerous new N-substituted Diprenorphine analogues (8a-f) with 7R absolute configuration were synthesized. Detailed pharmacological investigation of the prepared compounds may contribute to a better understanding of the structure-activity relationship of morphine alkaloids.
