162010-78-8Relevant articles and documents
Utility of the 2-Nitrobenzenesulfonamide Group as a Chemical Linker for Enhanced Extracellular Stability and Cytosolic Cleavage in siRNA-Conjugated Polymer Systems
Huang, Chih Hao,Takemoto, Hiroyasu,Nomoto, Takahiro,Tomoda, Keishiro,Matsui, Makoto,Nishiyama, Nobuhiro
, p. 19 - 22 (2017)
Herein we report the 2-nitrobenzenesulfonamide group as a new chemical linker that responds to the difference in redox potential across the cellular membrane, toward the construction of siRNA–polymer conjugates. PEG-conjugated to siRNA via the 2-nitrobenz
INDOLE DERIVATIVE USED AS CRTH2 INHIBITOR
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Paragraph 0309; 0311, (2019/06/07)
The present application discloses an indole as represented by formula (I) used as a CRTH2 inhibitor, and a pharmaceutically acceptable salt or tautomer of the indole, and an application of same in treating a disease related to a CRTH2 receptor.
Novel Sulfonaminoquinoline Hepcidin Antagonists
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, (2012/09/05)
The present invention relates to novel hepcidin antagonists, pharmaceutical compositions comprising them and the use thereof as medicaments for the use in the treatment of iron metabolism disorders, such as, in particular, iron deficiency diseases and anemias, in particular anemias in connection with chronic inflammatory diseases.