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59515-34-3

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59515-34-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 59515-34-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,5,1 and 5 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 59515-34:
(7*5)+(6*9)+(5*5)+(4*1)+(3*5)+(2*3)+(1*4)=143
143 % 10 = 3
So 59515-34-3 is a valid CAS Registry Number.

59515-34-3Relevant articles and documents

INDOLE DERIVATIVE USED AS CRTH2 INHIBITOR

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Paragraph 0309-0310, (2019/06/07)

The present application discloses an indole as represented by formula (I) used as a CRTH2 inhibitor, and a pharmaceutically acceptable salt or tautomer of the indole, and an application of same in treating a disease related to a CRTH2 receptor.

Utility of the 2-Nitrobenzenesulfonamide Group as a Chemical Linker for Enhanced Extracellular Stability and Cytosolic Cleavage in siRNA-Conjugated Polymer Systems

Huang, Chih Hao,Takemoto, Hiroyasu,Nomoto, Takahiro,Tomoda, Keishiro,Matsui, Makoto,Nishiyama, Nobuhiro

supporting information, p. 19 - 22 (2017/01/17)

Herein we report the 2-nitrobenzenesulfonamide group as a new chemical linker that responds to the difference in redox potential across the cellular membrane, toward the construction of siRNA–polymer conjugates. PEG-conjugated to siRNA via the 2-nitrobenz

COMPOUNDS HAVING A FUSED, BICYCLIC MOIETY FOR BINDING TO THE MINOR GROOVE OF DSDNA

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Page 62, (2010/02/09)

The present invention is directed to the means by which to alter the binding affinity and/or specificity of a compound with a sequence of DNA in the minor groove of a double-strand thereof. More particularly, the present invention is directed to a synthetic and/or non-naturally occurring compound (e.g., an analog of a polyamide oligomer or polymer) which contains at least one hydrogen bond donor moiety and at least one hydrogen bond acceptor moiety, wherein the latter moiety or "building block" has a fused, bicyclic structure which is heteroaromatic, said structure having a heteroatom therein which acts as a hydrogen bond acceptor to bind guanine in the minor groove of the dsDNA sequence, and which is incapable of forming a tautomer. In one particular embodiment of the synthetic and/or non-naturally occurring compound, the fused, bicyclic structure occupies an initial or first terminal position within the compound.

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