1620193-44-3

Upstream product

• 527-72-0 2-thiophenylcarboxylic acid 
• 98-88-4 benzoyl chloride 
• 65-85-0 benzoic acid 
• 1620194-08-2 N-(2-(pyridin-2-yl)propan-2-yl)benzamide-2-d₁ 
• 4551-39-7 2-deuteriobenzoic acid 
• 1620194-12-8 C₁₇H₁₈N₂O₃ 
• 583-55-1 1-Bromo-2-iodobenzene 
• 22069-99-4 1-bromo-2-deuterobenzene 

Downstream Products

• 69-72-7 salicylic acid 

Relevant academic research and scientific papers

Copper-/Silver-Mediated Arylation of C(sp2)-H Bonds with 2-Thiophenecarboxylic Acids

A copper/silver-mediated arylation of (hetero)aryl C-H bonds with 2-thiophenecarboxylic acids has been achieved. The protocol features a broad substrate scope and high functional group tolerance. Preliminary mechanistic studies indicate that a cascade pro

Copper-mediated hydroxylation of arenes and heteroarenes directed by a removable bidentate auxiliary

A copper-mediated C-H hydroxylation of arenes and heteroarenes using our newly developed PIP directing group has been developed. This procedure is scalable and compatible with a wide range of functional groups and heteroarenes, providing an operationally simple protocol for the synthesis of o-hydroxybenzamides. The hydroxylation of nicotinamides gave 4-oxo-1,4-dihydropyridine-3-carboxamides selectively. Preliminary mechanistic studies implicate that a basic ligand-enabled, irreversible, rate-determining CMD step is most likely involved in this process.