1620237-52-6Relevant academic research and scientific papers
B(C6F5)3-catalyzed Prins/Ritter reaction: A novel synthesis of hexahydro-1H-furo[3,4-c]pyranyl amide derivatives
Reddy, B.V. Subba,Ghanty, Supriya,Kishore, Ch.,Sridhar
, p. 4298 - 4301 (2014)
The coupling of aldehydes or ketones with (2-(4-methoxyphenyl)-4- methylenetetrahydrofuran-3-yl)methanol in the presence of nitriles under the influence of 5 mol % tris(pentaflourophenyl)borane at room temperature afforded a novel series of cis-fused hexahydro-1H-furo[3,4-c]pyran derivatives in good yields with high selectivity. This is the first report on the synthesis of hexahydro-1H-furo[3,4-c]pyranyl amide through a sequential Prins/Ritter reactions using B(C6F5)3 as a mild Lewis acid.
