1620578-11-1

Basic information

• Product Name: (S)-7-((3,5-difluoro-4-((2-(trifluoromethyl)pyridin-4-yl)oxy)benzyl)oxy)-1,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one
• Synonyms: (S)-7-((3,5-difluoro-4-((2-(trifluoromethyl)pyridin-4-yl)oxy)benzyl)oxy)-1,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one
• CAS NO: 1620578-11-1
• Molecular Weight: 468.383
• Mol File: 1620578-11-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-7-((3,5-difluoro-4-((2-(trifluoromethyl)pyridin-4-yl)oxy)benzyl)oxy)-1,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-7-((3,5-difluoro-4-((2-(trifluoromethyl)pyridin-4-yl)oxy)benzyl)oxy)-1,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one(1620578-11-1)
• EPA Substance Registry System: (S)-7-((3,5-difluoro-4-((2-(trifluoromethyl)pyridin-4-yl)oxy)benzyl)oxy)-1,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one(1620578-11-1)

Safety Data

• Hazardous Substances Data: 1620578-11-1(Hazardous Substances Data)

Upstream product

• 1620579-36-3 (S)-2-((2,6-dichloropyrimidin-4-yl)(methyl)amino)propan-1-ol 
• 170886-13-2 4-hydroxy-2-trifluoromethylpyridine 
• 204516-31-4 2-(trifluoromethyl)-4H-pyran-4-one 
• 1620579-54-5 3,5-difluoro-4-((2-(trifluoromethyl)pyridin-4-yl)oxy)benzaldehyde 
• 1620579-40-9 (S)-7-chloro-1,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one 
• 1620579-55-6 (3,5-difluoro-4-((2-(trifluoromethyl)pyridin-4-yl)oxy)phenyl)methanol 
• 1620579-38-5 (S)-4-chloro-6-((1-hydroxypropan-2-yl)(methyl)amino)pyrimidin-2(1H)-one 

Relevant articles and documents

COMPOUNDS

The present invention relates to novel compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease.