1621087-08-8Relevant academic research and scientific papers
Synthesis and immunological evaluation of self-adjuvanting MUC1-macrophage activating lipopeptide 2 conjugate vaccine candidates
McDonald, David M.,Wilkinson, Brendan L.,Corcilius, Leo,Thaysen-Andersen, Morten,Byrne, Scott N.,Payne, Richard J.
, p. 10273 - 10276 (2014)
We describe herein the synthesis and immunological evaluation of self-adjuvanting mucin 1 (MUC1)-macrophage activating lipopeptide 2 (MALP2) (glyco)peptide vaccine candidates. Vaccine constructs were shown to induce high titres of class-switched IgG antibodies in C57BL/6 mice after four immunisations despite the lack of a helper T cell epitope. This journal is the Partner Organisations 2014.
