1621431-73-9Relevant articles and documents
Iodine promoted synthesis of pyrido[2′,1′:2,3]imidazo[4,5-c]quinoline derivatives via oxidative decarboxylation of phenylacetic acid
Hindupur, Ramamohan,Jammula, Subba Rao,Jinkala, Rajesh,K. B, Shiva Kumar,Raghunadh, Akula,Rapolu, Venkateshwarlu,Satish P, Nikumbh,Tadiparthi, Krishnaji,Vidavalur, Siddaiah
, (2022/01/11)
An unprecedented and efficient molecular iodine promoted domino protocol for the synthesis of N polycyclic pyrido[2′,1′:2,3]imidazo[4,5-c]quinolines were reported from phenylacetic acid and 2-(imidazoheteroaryl)anilines. This methodology was also extended for the preparation of benzo[4′,5′]thiazolo [2′,3′:2,3]imidazo[4,5-c]isoquinolines in good yields. However, this protocol proceeds via a sequential decarboxylation of phenylacetic acid with I2/DMSO system followed by Pictet-Spengler cyclization in good yields.
One-pot sequential reactions featuring a copper-catalyzed amination leading to pyrido[2′,1′:2,3]imidazo[4,5-c]quinolines and dihydropyrido[2′,1′:2,3]imidazo[4,5-c]quinolines
Fan, Xue-Sen,Zhang, Ju,Li, Bin,Zhang, Xin-Ying
, p. 1281 - 1285 (2015/06/08)
Tetracyclic skeletons combining an imidazo[1,2-a]pyridine moiety with a quinoline framework such as pyrido[2′,1′:2,3]imidazo[4,5-b]quinoline are stimulating increasing interests since they are close isosteres of a series of powerful antiproliferative comp
