16217-56-4

Basic information

• Product Name: BOMBESIN 13-14
• Synonyms: BOMBESIN 13-14;L-LEU-L-MET NH2;H-Leu-Met-NH2
• CAS NO: 16217-56-4
• Molecular Formula: C₁₁H₂₃N₃O₂S
• Molecular Weight: 261.38
• Mol File: 16217-56-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 512.6±50.0 °C(Predicted)
• Appearance: /
• Density: 1.109±0.06 g/cm3(Predicted)
• Storage Temp.: -15°C
• PKA: 13.72±0.46(Predicted)
• CAS DataBase Reference: BOMBESIN 13-14(CAS DataBase Reference)
• NIST Chemistry Reference: BOMBESIN 13-14(16217-56-4)
• EPA Substance Registry System: BOMBESIN 13-14(16217-56-4)

Safety Data

• Hazardous Substances Data: 16217-56-4(Hazardous Substances Data)

Upstream product

• 33507-63-0 substance P 

Downstream Products

• 89671-31-8 H-Phe-Val-Gly-Leu-Met-NH₂ 
• 89680-70-6 Boc-Phe-Val-Gly-Leu-Met-NH₂ 
• 91682-54-1 C₅₉H₇₉N₉O₁₂S 
• 91682-51-8 C₅₃H₇₄N₈O₁₂S 
• 89671-25-0 Boc-Asp(OBzl)-Gln-Phe-Val-Gly-Leu-Met-NH₂ 
• 91682-59-6 C₅₂H₇₂N₈O₁₁S 
• 91682-52-9 (S)-3-Amino-N-((S)-2-benzyloxy-1-{(S)-1-[(S)-1-({[(S)-1-((S)-1-carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-methyl-propylcarbamoyl]-2-phenyl-ethylcarbamoyl}-ethyl)-succinamic acid benzyl ester 
• 89671-35-2 H-Asp(OBzl)-Gln-Phe-Val-Gly-Leu-Met-NH₂ 
• 91682-49-4 ((S)-2-Benzyloxy-1-{(S)-1-[(S)-1-({[(S)-1-((S)-1-carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-methyl-propylcarbamoyl]-2-phenyl-ethylcarbamoyl}-ethyl)-carbamic acid tert-butyl ester 
• 91682-58-5 ((S)-1-{(S)-1-[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-methyl-propylcarbamoyl]-2-phenyl-ethylcarbamoyl}-2-phenyl-ethyl)-carbamic acid tert-butyl ester 
• 89671-24-9 Boc-Gln-Phe-Val-Gly-Leu-Met-NH₂ 
• 91682-50-7 (S)-2-(2-{(S)-2-[(S)-2-((S)-2-Amino-3-benzyloxy-propionylamino)-3-phenyl-propionylamino]-3-methyl-butyrylamino}-acetylamino)-4-methyl-pentanoic acid ((S)-1-carbamoyl-3-methylsulfanyl-propyl)-amide 
• 89671-33-0 H-Gln-Phe-Val-Gly-Leu-Met-NH₂ 
• 91682-53-0 C₆₄H₈₇N₉O₁₄S 

Relevant articles and documents

SPECIFICITY AND MOLECULAR PROPERTIES OF PENICILLOLYSIN, A METALLOPROTEINASE FROM PENICILLUM CITRINUM

The specificity and mode of action of penicillolysin, a metalloproteinase from Penicillum citrinum, were investigated with several bioactive-oligopeptides.The enzyme showed a high affinity toward the Pro-X (X = Gln, Lys, Leu or Arg) bonds of substance P, dynorphin A (1-13), neurotensin and chicken brain pentapeptide, and the R-R bonds in dynorphin A and neurotensin.Preferential cleavages of bonds by the enzyme with hydrophobic amino acid residues at the P1 position were observed on the peptides used.The specificity of penicillolysin differs from that of other metallopropteinases.The Mr and pI were determined as 18000 and 9.6, respectively.The first 50 amino acids in the N-terminal region were TKETCSNASRKSALEKALSNTVKLANAAATAARSGSASKFSEYEKTTSSS.CD spectra on the hollo- and apo-enzymes of penicillolysin were studied.