162256-49-7

Basic information

• Product Name: 2-benzo<1,3>dioxol-5-yl-4-(4-methoxyphenyl)-4-oxobutyric acid methyl ester
• Synonyms: 2-benzo<1,3>dioxol-5-yl-4-(4-methoxyphenyl)-4-oxobutyric acid methyl ester
• CAS NO: 162256-49-7
• Molecular Weight: 342.348
• Mol File: 162256-49-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-benzo<1,3>dioxol-5-yl-4-(4-methoxyphenyl)-4-oxobutyric acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzo<1,3>dioxol-5-yl-4-(4-methoxyphenyl)-4-oxobutyric acid methyl ester(162256-49-7)
• EPA Substance Registry System: 2-benzo<1,3>dioxol-5-yl-4-(4-methoxyphenyl)-4-oxobutyric acid methyl ester(162256-49-7)

Safety Data

• Hazardous Substances Data: 162256-49-7(Hazardous Substances Data)

Upstream product

• 120-57-0 piperonal 
• 34419-97-1 (2-(4-methoxyphenyl)-2-oxoethyl)dimethylsulfonium bromide 
• 20912-79-2 4-methoxyphenacylidene dimethylsulphurane 
• 144309-50-2 (E)-1-(4-methoxyphenyl)-3-(3,4-methylenedioxyphenyl)prop-2-en-1-one 
• 67-56-1 methanol 
• 162256-48-6 2-(1,3-benzodioxol-5-yl)-1-(4-methoxyphenyl)-4-oxobutyronitrile 

Downstream Products

• 162256-50-0 3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(3,4,5-trimethoxy-benzyl)-5H-furan-2-one 
• 162256-35-1 2(5H)-furanone, 3-(1,3-benzodioxol-5-yl)-5-hydroxy-5-(4-methoxyphenyl)-4-(phenylmethyl)- 

Relevant articles and documents

Visible-Light-Promoted Polysubstituted Olefins Synthesis Involving Sulfur Ylides as Carbene Trapping Reagents

A blue-light-emitting diode (LED) promoted coupling of aryl diazoacetates with sulfur ylides is described. This protocol features mild conditions, good functional group tolerance, and broad substrate scope for both aryl diazoacetates with sulfur ylides. Under optimal reaction conditions, a wide range of trisubstituted olefins is obtained in moderate to good yield, which can be further transferred to other biologically important heterocycles after a two-step simple operation.

Butenolide endothelin antagonists with improved aqueous solubility

Continued development around our ET(A)-selective endothelin (ET) antagonist 1 (CI-1020) has led to the synthesis of analogues with improved aqueous solubility profiles. Poor solubility characteristics displayed by 1 required a complex buffered formulation

Discovery of a novel series of orally active non-peptide endothelin-A (ET(A)) receptor-selective antagonists

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