1623-06-9Relevant articles and documents
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Obata,Mukaiyama
, p. 1063 (1967)
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Obata et al.
, p. 1040,1041,1042 (1966)
Method for synthesis of n-propyl phosphoric acid
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Paragraph 0038; 0039; 0040, (2016/11/21)
The invention provides a preparation method for n-propyl phosphate. The preparation method comprises the following steps: (1) reacting tri-n-propyl phosphite with bromopropane under the catalysis of potassium iodide to obtain n-propyl di-n-propyl phosphate, wherein the reaction temperature is 50-70 DEG C; (2) reacting n-propyl di-n-propyl phosphate with trimethylsilyl chloride at the circumfluence temperature in an aprotic solvent under the catalysis of potassium bromide or potassium iodide to obtain n-propyl phosphate. The preparation method is easy to get the adopted raw materials, low in toxicity, less in by-products, easy to purify, low in cost and suitable for industrialized production. The reaction route of the preparation method is as follows: (as is shown in the Specification).
Regioselective phosphorylation of carbohydrates and various alcohols by bacterial acid phosphatases; probing the substrate specificity of the enzyme from Shigella flexneri
Van Herk, Teunie,Hartog, Aloysius F.,Van Der Burg, Alida M.,Wever, Ron
, p. 1155 - 1162 (2007/10/03)
Bacterial non-specific acid phosphatases normally catalyze the dephosphorylation of a variety of substrates. As shown previously the enzymes from Shigella flexneri and Salmonella enterica are also able to catalyze the phosphorylation of inosine to inosine monophosphate and D-glucose to D-glucose 6-phosphate (D-G6P) using cheap pyrophosphate as the phosphate donor. After optimization high yields (95%) are achieved in the latter reaction and we show here that it is possible to use these enzymes in a preparative manner. This prompted us to investigate by using 31P NMR and HPLC also the phosphorylation of a broad range of carbohydrates and alcohols. Many cyclic carbohydrates are phosphorylated in a regioselective manner. Non-cyclic carbohydrates are phosphorylated as well. Phosphorylation of linear alcohols, cyclic and aromatic alcohols is also possible. In all cases the acid phosphatase from Shigella prefers a primary alcohol function above a secondary one. We conclude that these enzymes are an attractive alternative to existing chemical and enzymatic methods in the phosphorylation of a broad range of compounds.
Poly-perfluoroalkyl-substituted alcohols and acids, and derivatives thereof
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, (2008/06/13)
Di-, tri- and poly-perfluoroalkyl-substituted alcohols and acids and derivatives thereof are described which are prepared from perfluoroalkyl iodides and di-, tri- or polyallyl alcohols or acids. These compounds contain two or more perfluoroalkyl-iodoalkyl or perfluoroalkyl-alkenyl groups and one or two alcohol or acid groups or derivatized alcohol or acid functions. They can be reacted with isocyanates, epoxy compounds, anhydrides, acids or acid derivatives to prepare a great variety of oil- and water-repellent compositions which are useful for oil- and water-repellent treatment of textiles, glass, paper, leather and other substrates.