162379-29-5Relevant academic research and scientific papers
Synthesis of (+)-coniceine via reductive photocyclization of dienamides: an entry to indolizidines
Hjelmgaard, Thomas,Gardette, Daniel,Tanner, David,Aitken, David J.
, p. 671 - 678 (2007/10/03)
This paper describes the establishment of a new synthetic route to the hydrobromide salt of (+)-coniceine 1 with high enantiopurity in five steps and 8% overall yield. The key step is the reductive photocyclization of an acyclic chiral dienamide, for whic
Synthesis of 5-Substituted Indolizidines and Approaches to 3- and 8-Substituted Indolizidines from a Common Intermediate Accessed via the Remote Dianion of 4-PSBA
Kiddle, James J.,Green, Diana L. C.,Thompson, Charles M.
, p. 2851 - 2864 (2007/10/02)
The dianion of 4-(phenylsulfonyl)butanoic acid (1: 4-PSBA) was used to prepare a pivotal intermediate 5 that was used in novel syntheses of indolizidines containing alkyl substituents in a variety of patterns at the 3-, 5- and, 8-positions.
