162439-95-4Relevant academic research and scientific papers
Synthesis of Thio-lignan Analogues, Bioequivalent Salvinal without Unfavored Aldehyde
Saito, Yohei,Kobayashi, Yukiko,Yoshida, Nanami,Goto, Masuo,Nakagawa-Goto, Kyoko
, p. 7092 - 7106 (2021/05/29)
The oxygen in the benzofuran (BF) of three antiproliferative natural neolignans, salvinal (1), obovaten (2), and 2-[7-methoxy-2-(4-methoxyphenyl)-3-methylbenzofuran-5-yl]ethanol (3), was replaced with sulfur to form the new biological scaffold benzothioph
Antileishmanial activity, cytotoxicity and QSAR analysis of synthetic dihydrobenzofuran lignans and related benzofurans
Miert, Sabine Van,Dyck, Stefaan Van,Schmidt, Thomas J.,Brun, Reto,Vlietinck, Arnold,Lemière, Guy,Pieters, Luc
, p. 661 - 669 (2007/10/03)
A series of synthetic dihydrobenzofuran lignans and related benzofurans were evaluated for their cytotoxicity in a screening panel consisting of various human tumour cell lines, and for their antiprotozoal activity against L. donovani (axenic amastigotes)
Studies on the preparation of bioactive lignans by oxidative coupling reaction. I. Preparation and lipid peroxidation inhibitory effect of benzofuran lignans related to schizotenuins
Maeda,Masuda,Tokoroyama
, p. 2500 - 2505 (2007/10/02)
The parent benzofuran lignan 4 of schizotenuins 1-3 and related compounds were efficiently prepared by a judicious use of the oxidative coupling reaction, and were tested for their inhibitory effects on lipid peroxidation in rat brain homogenate and rat l
