162459-97-4

Upstream product

• 160768-75-2 2'-O-(tert-butyldimethylsilyl)-4-O-deacetyl-2-O-debenzoyl-7-O-(triethylsilyl)paclitaxel 
• 156413-61-5 2'-(tert-butyldimethylsilyl)-7-(triethylsilyl)paclitaxel 
• 114655-02-6 2'-O-(tert-butyldimethylsilyl)paclitaxel 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 33069-62-4 taxol 
• 994-30-9 triethylsilyl chloride 
• 97-72-3 2-Methylpropionic anhydride 
• 160768-77-4 2'-O-(tert-butyldimethylsilyl)-7-O-triethylsilyl-2-debenzoyl-4-deacetyl-1,2-carbonato-paclitaxel 

Relevant academic research and scientific papers

Selective C-2 and C-4 deacylation and acylation of taxol: The first synthesis of a C-4 substituted taxol analogue

Hydrolytic procedures for selective 2-debenzoylation and 2,4-dideacylation of 2'-O-tert-butyldimethylsilyl-7-O-(triethylsilyl)taxol are reported. The first synthesis and biological evaluation of a 4-substituted analogue, 4-deacetyl-4-isobutanoyltaxol, is