162465-50-1

Basic information

• Product Name: Carbamic acid, [(2R)-3-hydroxy-2-methylpropyl]-, 1,1-dimethylethyl ester (9CI)
• Synonyms: Carbamic acid, [(2R)-3-hydroxy-2-methylpropyl]-, 1,1-dimethylethyl ester (9CI)
• CAS NO: 162465-50-1
• Molecular Formula: C9H19NO3
• Molecular Weight: 189.25206
• Product Categories: N-BOC
• Mol File: 162465-50-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 301.4±25.0 °C(Predicted)
• Appearance: /
• Density: 1.010±0.06 g/cm3(Predicted)
• PKA: 12.61±0.46(Predicted)
• CAS DataBase Reference: Carbamic acid, [(2R)-3-hydroxy-2-methylpropyl]-, 1,1-dimethylethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(2R)-3-hydroxy-2-methylpropyl]-, 1,1-dimethylethyl ester (9CI)(162465-50-1)
• EPA Substance Registry System: Carbamic acid, [(2R)-3-hydroxy-2-methylpropyl]-, 1,1-dimethylethyl ester (9CI)(162465-50-1)

Safety Data

• Hazardous Substances Data: 162465-50-1(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 245125-87-5 (2R)-3-Azido-2-methyl-1-propanol 
• 182486-32-4 (R)-methyl 3-{[(tert-butoxy)carbonyl]amino}-2-methylpropionate 
• 132696-45-8 (R)-2-{[(tert-butoxycarbonyl)amino]methyl}propionic acid 
• 518038-33-0 (2R)-(3,3-dimethoxy-2-methyl-propyl)-carbamic acid tert-butyl ester 
• 518038-34-1 (2-methyl-3-oxo-propyl)-carbamic acid tert-butyl ester 
• 104154-93-0 (R)-3-amino-2-methyl-1-propanol 

Downstream Products

• 245125-88-6 (2S,2'R)-benzyl 2-[(3'-{[(tert-butoxy)carbonyl]amino}-2'-methylpropinoyl)oxy]-4-methylpentanoate 
• 132696-45-8 (R)-2-{[(tert-butoxycarbonyl)amino]methyl}propionic acid 

Relevant articles and documents

TRIAZACYCLODODECANSULFONAMIDE ("TCD")-BASED PROTEIN SECRETION INHIBITORS

Provided herein are triazacyclododecansulfonamide ("TCD")-based protein secretion inhibitors, such as inhibitors of Sec61, methods for their preparation, related pharmaceutical compositions, and methods for using the same. For example, provided herein are compounds of Formula (I) and pharmaceutically acceptable salts and compositions including the same. The compounds disclosed herein may be used, for example, in the treatment of diseases including inflammation and/or cancer.

DIPEPTIDYL PEPTIDASE-IV INHIBITING COMPOUNDS, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT

The present invention relates to novel compounds exhibiting good inhibitory activity versus Dipeptidyl Peptidase-IV(DPP-IV), methods of preparing the same and pharmaceutical compositions containing the same as an active agent.

Highly enantioselective conjugate addition of dialkylzinc reagents to acyclic nitroalkenes: A catalytic route to β2-amino acids, aldehydes, and alcohols

Using chiral phosphoramidite ligand (S,R,R)-L1 in the conjugate addition to acyclic nitroalkenes for the first time, we obtained enantioselectivities up to 98%. The use of acyclic substrates with different dialkylzinc reagents provides a catalytic enantio