162472-69-7

Upstream product

• 65806-89-5 (R)-2-{[(benzyloxy)carbonyl]amino}-3-(4-methoxyphenyl)propionic acid 
• 162472-68-6 β-alanine 2-(trimethylsilyl)ethyl ester 
• 512178-52-8 3-Benzyloxycarbonylamino-propionic acid 2-trimethylsilanyl-ethyl ester 

Downstream Products

• 162600-54-6 arenastatin A 
• 162600-54-6 cryptophycin-24 
• 162472-70-0 3-[(R)-2-[2-(Diethoxy-phosphoryl)-acetylamino]-3-(4-methoxy-phenyl)-propionylamino]-propionic acid 2-trimethylsilanyl-ethyl ester 
• 162473-76-9 (S)-2-{3-[(R)-2-[2-(Diethoxy-phosphoryl)-acetylamino]-3-(4-methoxy-phenyl)-propionylamino]-propionyloxy}-4-methyl-pentanoic acid (E)-(1S,2R)-1-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2-methyl-4-phenyl-but-3-enyl ester 
• 162473-77-0 (S)-2-{3-[(R)-2-[2-(Diethoxy-phosphoryl)-acetylamino]-3-(4-methoxy-phenyl)-propionylamino]-propionyloxy}-4-methyl-pentanoic acid (E)-(1S,2R)-1-(2-hydroxy-ethyl)-2-methyl-4-phenyl-but-3-enyl ester 
• 1027309-65-4 (S)-2-{3-[(R)-2-[2-(Diethoxy-phosphoryl)-acetylamino]-3-(4-methoxy-phenyl)-propionylamino]-propionyloxy}-4-methyl-pentanoic acid (E)-(1S,2R)-2-methyl-1-(2-oxo-ethyl)-4-phenyl-but-3-enyl ester 
• 162472-71-1 3-[(R)-2-[(E)-4-((2S,3S,4R,5S)-4-Acetoxy-3-methyl-5-phenyl-tetrahydro-furan-2-yl)-but-2-enoylamino]-3-(4-methoxy-phenyl)-propionylamino]-propionic acid 2-trimethylsilanyl-ethyl ester 
• 162473-78-1 desepoxyarenastatin A 
• 162473-73-6 3-[(R)-2-[2-(Diethoxy-phosphoryl)-acetylamino]-3-(4-methoxy-phenyl)-propionylamino]-propionic acid 
• 1026148-52-6 3-[(R)-2-Amino-3-(4-methoxy-phenyl)-propionylamino]-propionic acid 2-trimethylsilanyl-ethyl ester 

Relevant academic research and scientific papers

A total synthesis of arenastatin A, an extremely potent cytotoxic depsipeptide, from the Okinawan marine sponge dysidea arenaria

An asymmetric synthesis of a cyclic depsipeptide arenastatin A (1), which was isolated from the marine sponge Dysidea arenaria and exhibited extremely potent cytotoxicity with IC50 5 pg/ml for KB cells, has been accomplished.

The absolute stereostructure of arenastatin A, a potent cytotoxic depsipeptide from the Okinawan marine sponge Dysidea arenaria

The absolute stereostructure of arenastatin A (1), which was isolated from the Okinawan marine sponge Dysidea arenaria, has been determined on the bases of NMR and synthetic studies. Arenastatin A (1) is a cyclic depsipeptide exhibiting extremely potent c